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Jadyn L Smith

Explore the profile of Jadyn L Smith including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Cardus D, Smith M, Vernaza A, Smith J, Del Buono B, Parajuli A, et al.
Genes (Basel) . 2024 Oct; 15(10). PMID: 39457392
: miR-506-3p has been demonstrated to be a strong inducer of neuroblastoma cell differentiation, highlighting the potential of applying miR-506-3p mimics to neuroblastoma differentiation therapy. However, the target genes of...
2.
Saucedo A, Subbarao M, Jemal M, Mesa-Diaz N, Smith J, Vernaza A, et al.
Int J Mol Sci . 2024 Aug; 25(15). PMID: 39125618
Caffeic acid phenethyl ester (CAPE) is a phenolic natural product with a wide range of biological activities, including anticancer activity; however, the ester group of CAPE is metabolically labile. The...
3.
Aksenov D, Smith J, Aksenov A, Prityko L, Aksenov N, Kuzminov I, et al.
Bioorg Med Chem Lett . 2024 Mar; 102:129681. PMID: 38432288
We previously studied 2-aryl-2-(3-indolyl)acetohydroxamates as potential agents against melanoma. These compounds were ineffective in a mouse melanoma xenograft model, most likely due to unfavorable metabolic properties, specifically due to glucuronidation...
4.
Vernaza A, Cardus D, Smith J, Partridge V, Baker A, Lewis E, et al.
J Cancer . 2024 Feb; 15(5):1153-1168. PMID: 38356706
We conducted a high-content screening (HCS) in neuroblastoma BE(2)-C cells to identify cell cycle regulators that control cell differentiation using a library of siRNAs against cell cycle-regulatory genes. We discovered...