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Jacqui Marzec

Explore the profile of Jacqui Marzec including associated specialties, affiliations and a list of published articles. Areas
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Articles 15
Citations 453
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Recent Articles
1.
Marzec J, Nadadur S
J Pharmacol Exp Ther . 2023 Oct; 388(2):560-567. PMID: 37863486
Inhaled toxicants are used for diverse purposes, ranging from industrial applications such as agriculture, sanitation, and fumigation to crowd control and chemical warfare, and acute exposure can induce lasting respiratory...
2.
Marzec J, Nadadur S
Toxicol Appl Pharmacol . 2022 Dec; 459:116343. PMID: 36526071
No abstract available.
3.
Cho H, Jedlicka A, Chang F, Marzec J, Bauer A, Kleeberger S
Antioxidants (Basel) . 2021 Sep; 10(9). PMID: 34573120
Ozone (O) is the predominant oxidant air pollutant associated with airway inflammation, lung dysfunction, and the worsening of preexisting respiratory diseases. We previously demonstrated the injurious roles of pulmonary immune...
4.
Marzec J, Cho H, High M, McCaw Z, Polack F, Kleeberger S
Physiol Genomics . 2019 Nov; 51(12):630-643. PMID: 31736414
Respiratory syncytial virus (RSV) causes severe lower respiratory tract disease in infants, young children, and susceptible adults. The pathogenesis of RSV disease is not fully understood, although toll-like receptor 4...
5.
Menendez D, Snipe J, Marzec J, Innes C, Polack F, Caballero M, et al.
J Clin Invest . 2019 Aug; 129(11):4875-4884. PMID: 31430261
The Toll-like receptor 8 (TLR8) has an important role in innate immune responses to RNA viral infections, including respiratory syncytial virus (RSV). We previously reported that TLR8 expression was increased...
6.
Antunes K, Fachi J, de Paula R, da Silva E, Pral L, Santos A, et al.
Nat Commun . 2019 Jul; 10(1):3273. PMID: 31332169
Severe respiratory syncytial virus (RSV) infection is a major cause of morbidity and mortality in infants <2 years-old. Here we describe that high-fiber diet protects mice from RSV infection. This...
7.
Ofman G, Caballero M, Alvarez Paggi D, Marzec J, Nowogrodzki F, Cho H, et al.
BMC Pediatr . 2019 Jul; 19(1):227. PMID: 31279333
Background: Premature birth is a growing and serious public health problem affecting more than one of every ten infants worldwide. Bronchopulmonary dysplasia (BPD) is the most common neonatal morbidity associated...
8.
High M, Cho H, Marzec J, Wiltshire T, Verhein K, Caballero M, et al.
EBioMedicine . 2016 Aug; 11:73-84. PMID: 27554839
Background: Respiratory syncytial virus (RSV) is the global leading cause of lower respiratory tract infection in infants. Nearly 30% of all infected infants develop severe disease including bronchiolitis, but susceptibility...
9.
Cho H, Marzec J, Kleeberger S
Free Radic Biol Med . 2015 Jun; 88(Pt B):362-372. PMID: 26117318
Nuclear factor (erythroid derived)-2 like 2 (NFE2L2), also known as nuclear factor erythroid 2 (NF-E2)-related factor 2 (Nrf2), is a ubiquitous transcription factor essential for protecting cells and tissues from...
10.
Caballero M, Serra M, Acosta P, Marzec J, Gibbons L, Salim M, et al.
J Clin Invest . 2015 Jan; 125(2):571-82. PMID: 25555213
While 30%-70% of RSV-infected infants develop bronchiolitis, 2% require hospitalization. It is not clear why disease severity differs among healthy, full-term infants; however, virus titers, inflammation, and Th2 bias are...