Jacques M Lignon
Overview
Explore the profile of Jacques M Lignon including associated specialties, affiliations and a list of published articles.
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5
Citations
35
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Recent Articles
1.
Raveau M, Lignon J, Nalesso V, Duchon A, Groner Y, Sharp A, et al.
PLoS Genet
. 2012 Jun;
8(5):e1002724.
PMID: 22693452
Down syndrome (DS) leads to complex phenotypes and is the main genetic cause of birth defects and heart diseases. The Ts65Dn DS mouse model is trisomic for the distal part...
2.
Lignon J, Bichler Z, Hivert B, Gannier F, Cosnay P, Del Rio J, et al.
Physiol Genomics
. 2008 Feb;
33(2):230-9.
PMID: 18303085
Congenital heart defects (CHD) are common in Down syndrome (DS, trisomy 21). Recently, cardiac sympathetic-parasympathetic imbalance has also been documented in DS adults free of any CHD. The KCNJ6 gene...
3.
Faucher F, Gannier F, Lignon J, Cosnay P, Malecot C
Am J Physiol Cell Physiol
. 2007 Oct;
294(1):C106-17.
PMID: 17942637
Although beta(2)-adrenoceptors represent 15-25% of beta-adrenoceptors in the guinea pig heart, their functionality is controversial. We assessed the inotropic effects of beta(2)-adrenoceptor partial agonists in right papillary muscles. Salbutamol induced...
4.
Alvarez M, Malecot C, Gannier F, Lignon J
Br J Pharmacol
. 2005 Jan;
144(1):17-27.
PMID: 15644865
Antimony (Sb) is the mainstay for the treatment of Leishmaniasis. It has serious, often lethal, cardiovascular side effects. The objective of this study was to examine the effects of Sb...
5.
Leroy J, Lignon J, Gannier F, Argibay J, Malecot C
Br J Pharmacol
. 2002 Feb;
135(3):721-34.
PMID: 11834620
The effects of 10 mM caffeine (CAF) on intramembrane charge movements (ICM) were studied in isolated guinea-pig ventricular heart cells with the whole-cell patch-clamp technique. In the presence of CAF,...