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Jacques Fantini

Explore the profile of Jacques Fantini including associated specialties, affiliations and a list of published articles. Areas
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Articles 123
Citations 3066
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Recent Articles
1.
Hikmat H, Le Targa L, Boschi C, Py J, Morand A, Lagier J, et al.
J Med Virol . 2025 Feb; 97(2):e70217. PMID: 39949218
HCoV-HKU1 diversity and evolution were scarcely studied. We performed next-generation sequencing (NGS) and analysis of HCoV-HKU1 genomes over 5 years. NGS used Illumina technology on NovaSeq 6000 following whole genome...
2.
Fantini J, Azzaz F, Di Scala C, Aulas A, Chahinian H, Yahi N
Pharmacol Ther . 2025 Jan; 267:108797. PMID: 39828029
The traditional model of protein structure determined by the amino acid sequence is today seriously challenged by the fact that approximately half of the human proteome is made up of...
3.
Lefebvre M, Chahinian H, La Scola B, Fantini J
Viruses . 2025 Jan; 16(12. PMID: 39772146
Most studies on the docking of ivermectin on the spike protein of SARS-CoV-2 concern the receptor binding domain (RBD) and, more precisely, the RBD interface recognized by the ACE2 receptor....
4.
Fantini J, Azzaz F, Bennai R, Yahi N, Chahinian H
Int J Mol Sci . 2024 Sep; 25(18). PMID: 39337677
Serotonin is distinct among synaptic neurotransmitters because it is amphipathic and released from synaptic vesicles at concentrations superior to its water solubility limit (270 mM in synaptic vesicles for a...
5.
Chahinian H, Yahi N, Fantini J
Int J Mol Sci . 2024 Aug; 25(16). PMID: 39201269
The synapse is a piece of information transfer machinery replacing the electrical conduction of nerve impulses at the end of the neuron. Like many biological mechanisms, its functioning is heavily...
6.
Incontro S, Musella M, Sammari M, Di Scala C, Fantini J, Debanne D
Physiol Rev . 2024 Jul; 105(1):137-207. PMID: 38990068
Lipids represent the most abundant molecular type in the brain, with a fat content of ∼60% of the dry brain weight in humans. Despite this fact, little attention has been...
7.
Colson P, Fantini J, Delerce J, Bader W, Levasseur A, Pontarotti P, et al.
Emerg Microbes Infect . 2024 Jun; 13(1):2368211. PMID: 38916498
The evolution of SARS-CoV-2, the agent of COVID-19, has been remarkable for its high mutation potential, leading to the appearance of variants. Some mutations have never appeared in the published...
8.
Colson P, Chaudet H, Delerce J, Pontarotti P, Levasseur A, Fantini J, et al.
J Infect . 2024 Apr; 88(5):106150. PMID: 38570164
Objectives: The SARS-CoV-2 pandemic and large-scale genomic surveillance provided an exceptional opportunity to analyze mutations that appeared over three years in viral genomes. Here we studied mutations and their epidemic...
9.
Fantini J, Matveeva M, Lefebvre M, Chahinian H
Life (Basel) . 2024 Mar; 14(3). PMID: 38541606
Defining life is an arduous task that has puzzled philosophers and scientists for centuries. Yet biology suffers from a lack of clear definition, putting biologists in a paradoxical situation where...
10.
Colson P, Delerce J, Pontarotti P, Devaux C, La Scola B, Fantini J, et al.
J Med Virol . 2024 Feb; 96(2):e29462. PMID: 38363015
Mutations associated with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) resistance to antiprotease nirmatrelvir were reported. We aimed to detect them in SARS-CoV-2 genomes and quasispecies retrieved in our institute...