Jacob Stauber
Overview
Explore the profile of Jacob Stauber including associated specialties, affiliations and a list of published articles.
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Articles
7
Citations
98
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0
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Recent Articles
1.
Taylor S, Stauber J, Bohorquez O, Tatsumi G, Kumari R, Chakraborty J, et al.
Nat Genet
. 2024 Sep;
56(10):2213-2227.
PMID: 39294495
Transcription factor (TF) DNA-binding dynamics govern cell fate and identity. However, our ability to pharmacologically control TF localization is limited. Here we leverage chemically driven binding site restriction leading to...
2.
Beenken A, Shen T, Jin G, Ghotra A, Xu K, Nesanir K, et al.
Am J Physiol Renal Physiol
. 2024 Sep;
327(5):F775-F787.
PMID: 39265081
Proximal tubule endocytosis is essential to produce protein-free urine as well as to regulate system-wide metabolic pathways, such as the activation of Vitamin D. We have determined that the proximal...
3.
Saygin C, Zhang P, Stauber J, Aldoss I, Sperling A, Weeks L, et al.
Blood Cancer Discov
. 2023 Dec;
5(3):164-179.
PMID: 38150184
Significance: CH is a precursor lesion for lymphoblastic leukemogenesis. ALL with MyM has distinct genetic and clinical characteristics, associated with adverse survival outcomes after chemotherapy. CH can precede ALL years...
4.
Shen T, Stauber J, Xu K, Jacunski A, Paragas N, Callahan M, et al.
JCI Insight
. 2022 Mar;
7(6).
PMID: 35230973
The current strategy to detect acute injury of kidney tubular cells relies on changes in serum levels of creatinine. Yet serum creatinine (sCr) is a marker of both functional and...
5.
Stauber J, Greally J, Steidl U
Blood
. 2020 Dec;
137(8):1013-1018.
PMID: 33275656
Hematological malignancies are an aggregate of diverse populations of cells that arise following a complex process of clonal evolution and selection. Recent approaches have facilitated the study of clonal populations...
6.
Xu K, Rosenstiel P, Paragas N, Hinze C, Gao X, Shen T, et al.
J Am Soc Nephrol
. 2016 Dec;
28(6):1729-1740.
PMID: 28028135
Two metrics, a rise in serum creatinine concentration and a decrease in urine output, are considered tantamount to the injury of the kidney tubule and the epithelial cells thereof (AKI)....
7.
Barasch J, Hollmen M, Deng R, Hod E, Rupert P, Abergel R, et al.
Nat Commun
. 2016 Nov;
7:12973.
PMID: 27796299
Iron overload damages many organs. Unfortunately, therapeutic iron chelators also have undesired toxicity and may deliver iron to microbes. Here we show that a mutant form (K3Cys) of endogenous lipocalin...