Jacob N Finkelstein
Overview
Explore the profile of Jacob N Finkelstein including associated specialties, affiliations and a list of published articles.
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59
Citations
1441
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Recent Articles
11.
Beach T, Johnston C, Groves A, Williams J, Finkelstein J
Exp Lung Res
. 2017 May;
43(3):134-149.
PMID: 28534660
Materials And Methods: In an established model of RIPF, C57BL/6J mice were exposed to 12.5 Gy thorax irradiation and sacrificed at 24 hours, 1, 4, 12, and 32 weeks following...
12.
Groves A, Johnston C, Misra R, Williams J, Finkelstein J
Int J Radiat Biol
. 2016 Aug;
92(12):754-765.
PMID: 27539247
Purpose: Thoracic irradiation injures lung parenchyma, triggering inflammation and immune cell activation, leading to pneumonitis and fibrosis. Macrophage polarization contributes to these processes. Since IL-4 promotes pro-fibrotic macrophage activation, its...
13.
Williams J, Calvi L, Chakkalakal J, Finkelstein J, OBanion M, Puzas E
Radiat Res
. 2016 Jun;
186(1):1-16.
PMID: 27332954
No abstract available.
14.
Groves A, Johnston C, Misra R, Williams J, Finkelstein J
Radiat Res
. 2015 Dec;
184(6):639-49.
PMID: 26632857
Exposure of the lung to radiation produces injury and inflammatory responses that result in microenvironmental alterations, which can promote the development of pneumonitis and/or pulmonary fibrosis. It has been shown...
15.
Rangel-Moreno J, Garcia-Hernandez M, Ramos-Payan R, Biear J, Hernady E, Sangster M, et al.
Radiat Res
. 2015 Sep;
184(4):352-66.
PMID: 26397175
The acute period after total body irradiation (TBI) is associated with an increased risk of infection, principally resulting from the loss of hematopoietic stem cells, as well as disruption of...
16.
Misra R, Johnston C, Groves A, DeDiego M, St Martin J, Reed C, et al.
Radiat Res
. 2015 Jun;
184(1):3-13.
PMID: 26114328
A number of investigators have suggested that exposure to low-dose radiation may pose a potentially serious health risk. However, the majority of these studies have focused on the short-term rather...
17.
Allen J, Liu X, Weston D, Prince L, Oberdorster G, Finkelstein J, et al.
Toxicol Sci
. 2014 Apr;
140(1):160-78.
PMID: 24690596
The brain appears to be a target of air pollution. This study aimed to further ascertain behavioral and neurobiological mechanisms of our previously observed preference for immediate reward (Allen, J....
18.
Manning C, Johnston C, Hernady E, Miller J, Reed C, Lawrence B, et al.
Radiat Res
. 2013 Apr;
179(6):617-29.
PMID: 23621375
Viral infections have been associated with exacerbation of disease in human cases of idiopathic pulmonary fibrosis. Since pulmonary fibrosis is a common outcome after irradiation to the lung, we hypothesized...
19.
Fazal F, Bijli K, Murrill M, Leonard A, Minhajuddin M, Anwar K, et al.
PLoS One
. 2013 Apr;
8(3):e59965.
PMID: 23555849
The pathogenesis of acute lung injury (ALI) involves bidirectional cooperation and close interaction between inflammatory and coagulation pathways. A key molecule linking coagulation and inflammation is the procoagulant thrombin, a...
20.
Johnston C, Manning C, Rangel-Moreno J, Randall T, Hernady E, Finkelstein J, et al.
Radiat Res
. 2013 Mar;
179(4):475-84.
PMID: 23496054
Significant differences exist between the physiology of the immature, neonatal lung compared to that of the adult lung that may affect acute and late responses to irradiation. Identifying these differences...