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Jacob Melchiors

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Citations 87
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Recent Articles
1.
Edstrom A, Makouei F, Wennervaldt K, Lomholt A, Kaltoft M, Melchiors J, et al.
Eur Arch Otorhinolaryngol . 2025 Feb; PMID: 39920508
Purpose: This clinical trial examined how the articifial intelligence (AI)-based diagnostics system S-Detect for Thyroid influences the ultrasound diagnostic work-up of thyroid ultrasound (US) performed by different US users in...
2.
von Buchwald J, Frendo M, Frithioff A, Britze A, Frederiksen T, Melchiors J, et al.
Ann Otol Rhinol Laryngol . 2024 Oct; 134(2):70-78. PMID: 39417404
Objective: Otoscopy is a key clinical examination used by multiple healthcare providers but training and testing of otoscopy skills remain largely uninvestigated. Simulator-based assessment of otoscopy skills exists, but evidence...
3.
Jakobsen K, Fenger Carlander A, Todsen T, Melchiors J, Paaske N, Ostergaard Madsen A, et al.
Clin Cancer Res . 2024 Mar; 30(10):2078-2084. PMID: 38441659
Purpose: No effective treatment exists for radiation-induced xerostomia. The objective of this study was to compare the effect of adipose-derived mesenchymal stem/stromal cell (ASC) injection, relative to placebo, on salivary...
4.
Warm J, Melchiors J, Kristensen T, Aabenhus K, Charabi B, Eberhard K, et al.
Laryngoscope Investig Otolaryngol . 2024 Feb; 9(1):e1201. PMID: 38362178
Objective: Surgeon-performed head and neck ultrasound (US) is increasingly used among otolaryngologists in office-based and surgical settings. However, it is unknown how formal US training affects otolaryngology residents' diagnostic workup...
5.
Jakobsen K, Fenger Carlander A, Gronhoj C, Todsen T, Melchiors J, Paaske N, et al.
Trials . 2023 Sep; 24(1):567. PMID: 37658468
Background: A predominant side effect of radiotherapy for head and neck cancer is salivary gland hypofunction and xerostomia leading to debilitating oral disorders and impaired quality of life (QoL). Intraglandular...
6.
Lynggaard C, Jersie-Christensen R, Juhl M, Jensen S, Gronhoj C, Melchiors J, et al.
Commun Med (Lond) . 2022 Dec; 2(1):160. PMID: 36496530
Background: Hyposalivation and xerostomia (dry mouth), are the leading site-effects to treatment of head and neck cancer. Currently, there are no effective therapies to alleviate radiation-induced hyposalivation. Adipose tissue-derived mesenchymal...
7.
Lynggaard C, Gronhoj C, Christensen R, Fischer-Nielsen A, Melchiors J, Specht L, et al.
Stem Cells Transl Med . 2022 Apr; 11(5):478-489. PMID: 35435231
No effective therapy exists for the most common long-term side effect of radiation therapy for head and neck cancer (HNC)-xerostomia. The objective was to evaluate safety and provide proof of...
8.
Todsen T, Bohr A, Hovgaard L, Eid R, Benfield T, Svendsen M, et al.
Diagnostics (Basel) . 2021 Nov; 11(11). PMID: 34829333
Proper specimen collection is the most important step to ensure accurate testing for the coronavirus disease 2019 (COVID-19) and other infectious diseases. Assessment of healthcare workers' upper respiratory tract specimen...
9.
Todsen T, Melchiors J, Larsen K, Charabi B, von Buchwald C
Ugeskr Laeger . 2021 Mar; 183(7). PMID: 33660597
Head and neck ultrasound examination is increasingly used as point-of-care imaging among clinicians from different specialities to improve the diagnostic workup and perform ultrasound-guided interventions. Ultrasound can provide immediate information...
10.
von Buchwald J, Frendo M, Guldager M, Melchiors J, Andersen S
Eur Arch Otorhinolaryngol . 2020 Sep; 278(7):2313-2320. PMID: 32909062
Purpose: At graduation from medical school, competency in otoscopy is often insufficient. Simulation-based training can be used to improve technical skills, but the suitability of the training model and assessment...