Jacob D McDonald
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Explore the profile of Jacob D McDonald including associated specialties, affiliations and a list of published articles.
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121
Citations
1841
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Recent Articles
11.
Sahay D, Lloyd S, Rivera J, Jezioro J, McDonald J, Pitiranggon M, et al.
Environ Res
. 2021 Mar;
196:110961.
PMID: 33675803
Background: Airborne polycyclic aromatic hydrocarbons (PAH) possess carcinogenic and endocrine disrupting properties linked to mammary tumorigenesis. These effects may be initiated during a prenatal period of susceptibility to PAH activation...
12.
Adivi A, Lucero J, Simpson N, McDonald J, Lund A
Toxicol Lett
. 2020 Dec;
339:39-50.
PMID: 33373663
Traffic-generated air pollutants have been correlated with alterations in blood-brain barrier (BBB) integrity, which is associated with pathologies in the central nervous system (CNS). Much of the existing literature investigating...
13.
Garner C, Wegerski C, Doyle-Eisele M, McDonald J, Sanders J, Moeller B, et al.
Toxicol Rep
. 2020 Aug;
7:883-892.
PMID: 32760656
2',2'''-Dithiobisbenzanilide (DTBBA) is a high-production-volume chemical used as a peptizing agent for rubber. The disposition and metabolism of [C]DTBBA were determined in male and female rats and mice following oral...
14.
Waidyanatha S, McDonald J, Sanders J, Doyle-Eisele M, Moeller B, Garner C
Xenobiotica
. 2020 Jun;
50(11):1341-1351.
PMID: 32501166
The specialty amine catalyst 2,2'-dimorpholinodiethyl ether (DMDEE) is a high-production volume chemical used in the production of flexible foam, high-resilient molded foam, and in coatings and adhesives. The disposition and...
15.
Fitch M, Phillippi D, Zhang Y, Lucero J, Pandey R, Liu J, et al.
Environ Res
. 2019 Nov;
181:108913.
PMID: 31753468
Air pollution exposure is known to contribute to the progression of cardiovascular disease (CVD) and there is increasing evidence that dysbiosis of the gut microbiome may also play a role...
16.
Mutlu E, Garner C, Wegerski C, McDonald J, McIntyre B, Doyle-Eisele M, et al.
Xenobiotica
. 2019 Oct;
50(6):689-704.
PMID: 31613170
2-Hydroxy-4-methoxybenzophenone (HMB) is a common ingredient in personal care products and used as an UV stabilizer. In these studies, disposition and metabolism of [C]HMB in rats and mice was assessed...
17.
Zychowski K, Steadman Tyler C, Sanchez B, Harmon M, Liu J, Irshad H, et al.
Cardiovasc Toxicol
. 2019 Aug;
20(3):211-221.
PMID: 31410643
Roadside proximity and exposure to mixed vehicular emissions (MVE) have been linked to adverse pulmonary and vascular outcomes. However, because of the complex nature of the contribution of particulate matter...
18.
Kuehl P, Chand R, McDonald J, Hava D, DeHaan W
AAPS PharmSciTech
. 2019 Jul;
20(6):242.
PMID: 31264190
The utilization of ferrets as a non-clinical model for disease is rapidly increasing within drug development. Many of these models include respiratory diseases that involve targeted drug delivery via nose-only...
19.
Suwannasual U, Lucero J, Davis G, McDonald J, Lund A
Toxicol Sci
. 2019 May;
170(2):525-535.
PMID: 31132127
Exposure to traffic-generated pollution is associated with alterations in blood-brain barrier (BBB) integrity and exacerbation of cerebrovascular disorders. Angiotensin (Ang) II signaling through the Ang II type 1 (AT1) receptor...
20.
Lewine J, Weber W, Gigliotti A, McDonald J, Doyle-Eisele M, Bangera N, et al.
Neurotoxicology
. 2018 Sep;
69:37-46.
PMID: 30172622
Rats poisoned with sarin enter into ahyper-cholinergic crisis characterized by excessive salivation, respiratory distress, tremors, seizures, and death. Through the use of rescue medications and an anticonvulsant, death can be...