Jackie Cheng
Overview
Explore the profile of Jackie Cheng including associated specialties, affiliations and a list of published articles.
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Articles
6
Citations
283
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0
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Recent Articles
1.
Kantak S, Faggioni R, Cai A, Bhatti M, Li J, Vainshtein I, et al.
Mol Cancer Ther
. 2024 Nov;
24(2):251-260.
PMID: 39494690
Tissue factor (TF) is overexpressed in various cancers and is typically associated with poor clinical outcomes. XB002 is an anti-TF antibody-drug conjugate designed to selectively deliver a cytotoxic payload to...
2.
Cheng J, Liang M, Carvalho M, Tigue N, Faggioni R, Roskos L, et al.
Antibodies (Basel)
. 2020 Sep;
9(3).
PMID: 32961882
Amplification and overexpression of HER2 (human epidermal growth factor receptor 2), an ErbB2 receptor tyrosine kinase, have been implicated in human cancer and metastasis. A bispecific tetravalent anti-HER2 antibody (anti-HER2-Bs),...
3.
Vainshtein I, Roskos L, Cheng J, Sleeman M, Wang B, Liang M
Pharm Res
. 2014 Sep;
32(1):286-99.
PMID: 25208874
Purpose: Measurement of internalization of biopharmaceuticals targeting cell surface proteins can greatly facilitate drug development. The objective of this study was to develop a reliable method for determination of internalization...
4.
Xin X, Gfeller D, Cheng J, Tonikian R, Sun L, Guo A, et al.
Mol Syst Biol
. 2013 Apr;
9:652.
PMID: 23549480
Src homology 3 (SH3) domains bind peptides to mediate protein-protein interactions that assemble and regulate dynamic biological processes. We surveyed the repertoire of SH3 binding specificity using peptide phage display...
5.
Cheng J, Grassart A, Drubin D
Mol Biol Cell
. 2012 Jun;
23(15):2891-904.
PMID: 22675027
Myosin 1E (Myo1E) is recruited to sites of clathrin-mediated endocytosis coincident with a burst of actin assembly. The recruitment dynamics and lifetime of Myo1E are similar to those of tagged...
6.
Doyon J, Zeitler B, Cheng J, Cheng A, Cherone J, Santiago Y, et al.
Nat Cell Biol
. 2011 Feb;
13(3):331-7.
PMID: 21297641
Clathrin-mediated endocytosis (CME) is the best-studied pathway by which cells selectively internalize molecules from the plasma membrane and surrounding environment. Previous live-cell imaging studies using ectopically overexpressed fluorescent fusions of...