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Jack A Bryant

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Citations 435
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Recent Articles
11.
Bryant J, Cadby I, Chong Z, Boelter G, Sevastsyanovich Y, Morris F, et al.
J Bacteriol . 2020 Oct; 203(2). PMID: 33106348
The asymmetric Gram-negative outer membrane (OM) is the first line of defense for bacteria against environmental insults and attack by antimicrobials. The key component of the OM is lipopolysaccharide, which...
12.
Seabright A, Fine N, Barlow J, Lord S, Musa I, Gray A, et al.
FASEB J . 2020 Mar; 34(5):6284-6301. PMID: 32201986
Mitophagy is a key process regulating mitochondrial quality control. Several mechanisms have been proposed to regulate mitophagy, but these have mostly been studied using stably expressed non-native proteins in immortalized...
13.
Dominguez-Medina C, Perez-Toledo M, Schager A, Marshall J, Cook C, Bobat S, et al.
Nat Commun . 2020 Feb; 11(1):851. PMID: 32051408
Lipopolysaccharide (LPS) O-antigen (O-Ag) is known to limit antibody binding to surface antigens, although the relationship between antibody, O-Ag and other outer-membrane antigens is poorly understood. Here we report, immunization...
14.
Santos F, Yamamoto D, Abe C, Bryant J, Hernandes R, Kitamura F, et al.
Front Microbiol . 2019 Jul; 10:1527. PMID: 31338081
The intimin protein is the major adhesin involved in the intimate adherence of atypical enteropathogenic (aEPEC) strains to epithelial cells, but little is known about the structures involved in their...
15.
Hughes G, Hall S, Laxton C, Sridhar P, Mahadi A, Hatton C, et al.
Nat Microbiol . 2019 Jun; 4(10):1692-1705. PMID: 31235958
The Mla pathway is believed to be involved in maintaining the asymmetrical Gram-negative outer membrane via retrograde phospholipid transport. The pathway is composed of three components: the outer membrane MlaA-OmpC/F...
16.
Cooke K, Browning D, Lee D, Blair J, McNeill H, Huber D, et al.
Biochem Soc Trans . 2019 Jun; 47(3):839-845. PMID: 31189732
The activity of any bacterial promoter is generally supposed to be set by its base sequence and the different transcription factors that bind in the local vicinity. Here, we review...
17.
Santos F, Richardson E, Bryant J, Yamamoto D, Elias W, Gomes T, et al.
Microbiol Resour Announc . 2018 Dec; 7(22). PMID: 30533858
The number of diarrhea cases caused by atypical enteropathogenic Escherichia coli (aEPEC) has been increasing worldwide. Here, we report the draft whole-genome sequences of 10 aEPEC strains isolated in Brazil....
18.
Morris F, Wells T, Bryant J, Schager A, Sevastsyanovich Y, Squire D, et al.
Infect Immun . 2018 Sep; 86(11). PMID: 30201701
Mutations in σ-regulated lipoproteins have previously been shown to impact bacterial viability under conditions of stress and during infection. YraP is conserved across a number of Gram-negative pathogens, including ,...
19.
Bryant J, Lee D
Methods Mol Biol . 2017 Aug; 1624:3-16. PMID: 28842871
Homologous recombination methods enable modifications to be made to the bacterial chromosome. Commonly, the λ phage RED proteins are employed as a site-specific recombinase system, to facilitate recombination of linear...
20.
Isom G, Davies N, Chong Z, Bryant J, Jamshad M, Sharif M, et al.
Sci Rep . 2017 Aug; 7(1):8608. PMID: 28819315
Bacterial proteins with MCE domains were first described as being important for Mammalian Cell Entry. More recent evidence suggests they are components of lipid ABC transporters. In Escherichia coli, the...