Jacek R Wisniewski
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Explore the profile of Jacek R Wisniewski including associated specialties, affiliations and a list of published articles.
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131
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9460
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Recent Articles
1.
Pousa S, Ramos-Bermudez P, Besada V, Cabrales-Rico A, Guirola Cruz O, Garay H, et al.
Analyst
. 2025 Jan;
150(6):1091-1102.
PMID: 39817672
Keyhole limpet haemocyanins (KLH1 and KLH2) from , are multi-subunit oxygen-carrying metalloproteins of approximately 3900 amino acids, that are widely used as carrier proteins in conjugate vaccines and in immunotherapy....
2.
Hernandez-Cedeno M, Rodriguez-Ulloa A, Ramos Y, Gonzalez L, Serrano-Diaz A, Zettl K, et al.
Biomedicines
. 2025 Jan;
12(12.
PMID: 39767648
Jusvinza is an immunomodulatory drug composed of an altered peptide ligand (APL) designed from a novel CD4+ T cell epitope of human heat shock protein 60 (HSP60), an autoantigen involved...
3.
Grzes M, Jaiswar A, Grochowski M, Wojtys W, Kazmierczak W, Olesinski T, et al.
Cell Death Dis
. 2024 Aug;
15(8):638.
PMID: 39217152
The major driver oncogenes MYC, mutant KRAS, and mutant TP53 often coexist and cooperate to promote human neoplasia, which results in anticancer therapeutic opportunities within their downstream molecular programs. However,...
4.
Rodriguez-Ulloa A, Rosales M, Ramos Y, Guirola O, Gonzalez L, Wisniewski J, et al.
J Proteomics
. 2024 Aug;
307:105269.
PMID: 39098729
Quantitative phosphoproteomic data has mostly been reported from experiments comparing relative phosphopeptides intensities in two or more different conditions, while the ideal parameter to compare is phosphopeptides occupancies. This term...
5.
Drulis-Fajdasz D, Krzystyniak A, Puscian A, Pytys A, Gostomska-Pampuch K, Pudelko-Malik N, et al.
Aging Cell
. 2023 Jul;
22(9):e13928.
PMID: 37522798
Inhibition of glycogen breakdown blocks memory formation in young animals, but it stimulates the maintenance of the long-term potentiation, a cellular mechanism of memory formation, in hippocampal slices of old...
6.
Carvalho L, Teigas-Campos P, Jorge S, Protti M, Mercolini L, Dhir R, et al.
Talanta
. 2023 Jul;
266(Pt 1):124953.
PMID: 37490822
Normalization is a crucial step in proteomics data analysis as it enables data adjustment and enhances comparability between datasets by minimizing multiple sources of variability, such as sampling, sample handling,...
7.
Harwood M, Zettl K, Weinheimer M, Pilla-Reddy V, Shen H, Jacobs F, et al.
Mol Pharm
. 2023 Jun;
20(7):3505-3518.
PMID: 37283406
Madin-Darby canine kidney (MDCK) cells are widely used to study epithelial cell functionality. Their low endogenous drug transporter protein levels make them an amenable system to investigate transepithelial permeation and...
8.
Vazquez-Blomquist D, Hardy-Sosa A, Baez S, Besada V, Palomares S, Guirola O, et al.
Cells
. 2022 Dec;
11(24).
PMID: 36552831
HeberFERON, a co-formulation of Interferon (IFN)-α2b and IFN-γ, has effects on skin cancer and other solid tumors. It has antiproliferative effects over glioblastoma multiform (GBM) clones and cultured cell lines,...
9.
Gostomska-Pampuch K, Wisniewski J, Sowinski K, Gruszecki W, Gamian A, Staniszewska M
Int J Mol Sci
. 2022 Nov;
23(21).
PMID: 36361822
MAGE (melibiose-derived advanced glycation end-product) is the glycation product generated in the reaction of a model protein with melibiose. The in vivo analog accumulates in several tissues; however, its origin...
10.
Oron M, Grochowski M, Jaiswar A, Legierska J, Jastrzebski K, Nowak-Niezgoda M, et al.
Cell Rep
. 2022 Sep;
40(13):111428.
PMID: 36170818
Proteasome machinery is a major proteostasis control system in human cells, actively compensated upon its inhibition. To understand this compensation, we compared global protein landscapes upon the proteasome inhibition with...