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Jacek Jasiecki

Explore the profile of Jacek Jasiecki including associated specialties, affiliations and a list of published articles. Areas
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Articles 18
Citations 137
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Recent Articles
1.
Stec A, Targonska M, Jaikishan S, Chen R, Mucha P, Czyrski G, et al.
Drug Deliv . 2024 Dec; 32(1):2439272. PMID: 39663752
Extracellular vesicles (EVs) are an experimental class of drug carriers. Alternative sources of EVs are currently being explored to overcome limitations related to their manufacturing from mesenchymal stem cells. In...
2.
Jasiecki J, Targonska M, Janaszak-Jasiecka A, Kalinowski L, Waleron K, Wasag B
Chem Biol Interact . 2023 Oct; 386:110783. PMID: 37884182
Alzheimer's disease (AD) pathogenesis has been attributed to extracellular aggregates of amyloid β (Aβ) plaques and neurofibrillary tangles in the human brain. It has been reported that butyrylcholinesterase (BChE) also...
3.
Jasiecki J, Targonska M, Janaszak-Jasiecka A, Chmara M, Zuk M, Kalinowski L, et al.
Int J Mol Sci . 2023 Jul; 24(14). PMID: 37511194
Familial hypercholesterolemia (FH) is an autosomal-dominant disorder caused mainly by substitutions in the low-density lipoprotein receptor () gene, leading to an increased risk of premature cardiovascular diseases. Tremendous advances in...
4.
Stec A, Targonska M, Karkosinska E, Slowik M, Ploska A, Kalinowski L, et al.
Anal Bioanal Chem . 2023 May; 415(16):3167-3176. PMID: 37160422
Despite the abundance of available cell lines, nearly 70% of all recombinant therapeutic proteins today are produced in Chinese hamster ovary (CHO) cells. The impact of protein overproduction on the...
5.
Jonca J, Waleron M, Czaplewska P, Bogucka A, Stec A, Dziomba S, et al.
Int J Mol Sci . 2021 Nov; 22(22). PMID: 34830459
Bacteria of genus are Gram-negative rods of the family . They are the causative agent of soft rot diseases of crops and ornamental plants. However, their virulence mechanisms are not...
6.
Jasiecki J, Szczoczarz A, Cysewski D, Lewandowski K, Skowron P, Waleron K, et al.
Int J Mol Sci . 2021 Oct; 22(19). PMID: 34639003
Measuring various biochemical and cellular components in the blood is a routine procedure in clinical practice. Human serum contains hundreds of diverse proteins secreted from all cells and tissues in...
7.
Jasiecki J, Targonska M, Wasag B
Int J Mol Sci . 2021 Mar; 22(4). PMID: 33670778
Alzheimer's disease (AD), the most common form of dementia in elderly individuals, is marked by progressive neuron loss. Despite more than 100 years of research on AD, there is still...
8.
Jasiecki J, Wasag B
Biomolecules . 2019 Oct; 9(10). PMID: 31601022
Late-onset Alzheimer's disease (AD) is clinically characterized by a progressive decline of memory and other cognitive functions leading to the loss of the ability to perform everyday activities. Only a...
9.
Jasiecki J, Zuk M, Krawczynska N, Jonca J, Szczoczarz A, Lewandowski K, et al.
Chem Biol Interact . 2019 May; 307:154-157. PMID: 31071335
Butyrylcholinesterase (BChE) is a serine hydrolase widely distributed throughout the body. It provides protection against administrated or inhaled poisons by hydrolyzing or sequestering the toxic compounds. The most frequent genetic...
10.
Jasiecki J, Limon-Sztencel A, Zuk M, Chmara M, Cysewski D, Limon J, et al.
Sci Rep . 2019 Mar; 9(1):5223. PMID: 30914707
While the life expectancy of the population has increased, Alzheimer's disease (AD) has emerged as one of the greatest health problems of old age. AD is characterized by neuronal loss...