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Jacek Jasiecki

Explore the profile of Jacek Jasiecki including associated specialties, affiliations and a list of published articles. Areas
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Articles 18
Citations 137
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Recent Articles
11.
Krawczynska N, Wierzba J, Jasiecki J, Wasag B
BMC Med Genet . 2019 Jan; 20(1):1. PMID: 30606125
Background: Cornelia de Lange syndrome (CdLS), a rare, multisystemic disorder, has been linked to genetic alterations in NIPBL, SMC1A, SMC3, HDAC8, and RAD21 genes. Approximately 60% of CdLS patients harbor...
12.
Jasiecki J, Jonca J, Zuk M, Szczoczarz A, Janaszak-Jasiecka A, Lewandowski K, et al.
Chem Biol Interact . 2016 Apr; 259(Pt B):70-77. PMID: 27109752
Butyrylcholinesterase (BChE) activity assay and inhibitor phenotyping can help to identify individuals at risk of prolonged paralysis following the administration of neuromuscular blocking agents, like succinylcholine, pesticides and nerve agents....
13.
Jonca J, Zuk M, Wasag B, Janaszak-Jasiecka A, Lewandowski K, Wielgomas B, et al.
PLoS One . 2015 Oct; 10(10):e0139480. PMID: 26444431
Butyrylcholinesterase (BChE) activity assay and inhibitor phenotyping can help to identify patients at risk of prolonged paralysis following the administration of neuromuscular blocking agents. The assay plays an important role...
14.
Zylicz-Stachula A, Zolnierkiewicz O, Jasiecki J, Skowron P
BMC Genomics . 2013 Jun; 14:370. PMID: 23724933
Background: Genomics and metagenomics are currently leading research areas, with DNA sequences accumulating at an exponential rate. Although enormous advances in DNA sequencing technologies are taking place, progress is frequently...
15.
Jasiecki J, Wegrzyn G
FEMS Microbiol Lett . 2006 Jul; 261(1):118-22. PMID: 16842368
In Escherichia coli, RNA polyadenylation is catalyzed mainly by poly(A) polymerase I (PAP I). Here we demonstrate that a PAP I variant with a C-terminal His tag (PAP I-His) can...
16.
Jasiecki J, Wegrzyn G
Plasmid . 2005 Dec; 55(2):169-72. PMID: 16330100
Escherichia coli pcnB gene was discovered as a regulator of ColE1 plasmid copy number about 20 years ago. Further studies indicated that this gene codes for poly(A) polymerase I (PAP...
17.
Jasiecki J, Wegrzyn G
Biochem Biophys Res Commun . 2005 Mar; 329(2):598-602. PMID: 15737627
Poly(A) polymerase I (PAP I), the pcnB gene product, is the main enzyme responsible for RNA polyadenylation in Escherichia coli. Polyadenylated RNA molecules are rapidly degraded by a multiprotein complex...
18.
Jasiecki J, Wegrzyn G
EMBO Rep . 2003 Mar; 4(2):172-7. PMID: 12612607
RNA polyadenylation occurs not only in eukaryotes but also in bacteria. In prokaryotes, polyadenylated RNA molecules are usually degraded more efficiently than non-modified transcripts. Here we demonstrate that two transcripts,...