J Zapf
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Explore the profile of J Zapf including associated specialties, affiliations and a list of published articles.
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Articles
227
Citations
3170
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Recent Articles
11.
Mazerbourg S, Overgaard M, Oxvig C, Christiansen M, Conover C, Laurendeau I, et al.
Endocrinology
. 2001 Nov;
142(12):5243-53.
PMID: 11713222
IGF binding protein-4 (IGFBP-4) proteolytic degradation is a common feature of preovulatory follicles from human, ovine, bovine, porcine, and equine ovary. In all these species, the protease is a zinc-dependent...
12.
Schmid C, Ghirlanda-Keller C, Zapf J
Eur J Endocrinol
. 2001 Jul;
145(2):213-21.
PMID: 11454519
Objective: Insulin-like growth factor binding protein-3 (IGFBP-3) inhibits cell growth. Previous reports have suggested the existence of plasma membrane IGFBP-3 receptors that could mediate direct, IGF-independent effects. Thus far, however,...
13.
Meinel L, Illi O, Zapf J, Malfanti M, Peter Merkle H, Gander B
J Control Release
. 2001 Feb;
70(1-2):193-202.
PMID: 11166419
This study aimed at developing a controlled drug delivery system for recombinant human insulin-like growth factor-I (IGF-I) for localized delivery in bone healing. IGF-I was microencapsulated into an end-group uncapped...
14.
Bentrem D, Dardes R, Liu H, Zapf J, Jordan V
Endocrinology
. 2001 Feb;
142(2):838-46.
PMID: 11159857
Tamoxifen is the endocrine treatment of choice for all stages of estrogen receptor (ER)-positive breast cancer, and it is the first drug approved to reduce the incidence of breast cancer...
15.
Zoidis E, Zapf J, Schmid C
Mol Cell Endocrinol
. 2000 Nov;
168(1-2):41-51.
PMID: 11064151
Phosphate regulating gene with homology to endopeptidases on the X chromosome (Phex) inactivating mutations cause X-linked hypophosphatemia (XLH). The disorder is characterized by decreased renal phosphate (Pi) reabsorption in both...
16.
Zapf J, Sen U, Madhusudan , Hoch J, Varughese K
Structure
. 2000 Sep;
8(8):851-62.
PMID: 10997904
Background: Spo0F and Spo0B specifically exchange a phosphoryl group in a central step of the phosphorelay signal transduction system that controls sporulation in Bacilli. Spo0F belongs to the superfamily of...
17.
Donath M, FROESCH E, Zapf J
Growth Horm IGF Res
. 2000 Sep;
8 Suppl B:167-70.
PMID: 10990156
No abstract available.
18.
Reinecke M, Schmid A, Hunziker E, Zapf J
Endocrinology
. 2000 Aug;
141(8):2847-53.
PMID: 10919271
Conflicting data exist as to whether insulin-like growth factor I (IGF-I) messenger RNA (mRNA) and peptide are expressed within chondrocytes. This question is pertinent to the mode of GH action...
19.
Mazerbourg S, Zapf J, Bar R, Brigstock D, Monget P
Biol Reprod
. 2000 Jul;
63(2):390-400.
PMID: 10906042
We recently showed that insulin-like growth factor-binding protein-4 (IGFBP-4) proteolytic degradation in ovine preovulatory ovarian follicles is IGF-dependent and regulated by the heparin-binding domain (HBD) from IGFBP-3 and from connective...
20.
Empen K, Otto C, Muller-Hocker J, Zapf J, Schwandt P
J Clin Oncol
. 2000 Mar;
18(7):1594-6.
PMID: 10735907
No abstract available.