J W Pettegrew
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Explore the profile of J W Pettegrew including associated specialties, affiliations and a list of published articles.
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94
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1772
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Recent Articles
11.
Levine J, Panchalingam K, McClure RJ2 , Gershon S, Pettegrew J
J Neural Transm (Vienna)
. 2000 Sep;
107(7):843-8.
PMID: 11005549
Analysis of cerebrospinal fluid (CSF) metabolites can provide data regarding CNS involvement in neurologic and psychiatric illness. However, there is lack of research into the effect of processing and storage...
12.
Keshavan M, Stanley J, Pettegrew J
Biol Psychiatry
. 2000 Sep;
48(5):369-80.
PMID: 10978720
Magnetic resonance spectroscopy allows investigation of in vivo neurochemical pathology of schizophrenia. "First generation" studies, focusing on phosphorus and proton magnetic resonance spectroscopy, have suggested alterations in membrane phospholipid metabolism...
13.
Stanley J, Pettegrew J, Keshavan M
Biol Psychiatry
. 2000 Sep;
48(5):357-68.
PMID: 10978719
Our knowledge of the biological basis of schizophrenia has significantly increased with the contribution of in vivo proton and phosphorus magnetic resonance spectroscopy (MRS), a noninvasive tool that can assess...
14.
Levine J, Panchalingam K, Rapoport A, Gershon S, McClure R, Pettegrew J
Biol Psychiatry
. 2000 Apr;
47(7):586-93.
PMID: 10745050
Background: There is increasing evidence for an association between alterations of brain glutamatergic neurotransmission and the pathophysiology of affective disorders. Methods: We studied the association between cerebrospinal fluid (CSF) metabolites,...
15.
DeQuardo J, Keshavan M, Bookstein F, Bagwell W, Green W, Sweeney J, et al.
Biol Psychiatry
. 1999 Jun;
45(10):1321-8.
PMID: 10349039
Background: The goal of this investigation was to utilize landmark-based shape analysis and image averaging to determine the sites and extent of specific structural changes in first-episode schizophrenia. Methods: Neuroanatomic...
16.
Klunk W, Panchalingam K, McClure R, Stanley J, Pettegrew J
Neurobiol Aging
. 1999 Apr;
19(6):511-5.
PMID: 10192209
Alterations in phospholipid metabolites are a characteristic abnormality of Alzheimer's disease (AD). Many of these alterations have been demonstrated by magnetic resonance spectroscopy (MRS) studies of postmortem tissue. Phosphodiesters appear...
17.
Klunk W, Debnath M, Koros A, Pettegrew J
Life Sci
. 1998 Nov;
63(20):1807-14.
PMID: 9820124
Increasing evidence suggests that deposition of amyloid-beta (A beta) peptide leads to neurodegeneration in Alzheimer's disease. Congo red, a histologic dye that binds to amyloid has previously been shown to...
18.
Keshavan M, Haas G, Kahn C, Aguilar E, Dick E, Schooler N, et al.
J Psychiatr Res
. 1998 Oct;
32(3-4):161-7.
PMID: 9793869
Accumulating evidence suggests alterations in brain structure, especially in the prefrontal and temporal cortex, in schizophrenia. Previous studies examining the progression of brain structural alterations in schizophrenia have led to...
19.
Keshavan M, Schooler N, Sweeney J, Haas G, Pettegrew J
Br J Psychiatry Suppl
. 1998 Oct;
172(33):60-5.
PMID: 9764128
Background: Studies of first-episode patients allow investigation of the biological basis of psychotic disorders without the potential confounds of prior treatment and illness chronicity. Prospective studies of this population can...
20.
Keshavan M, Rosenberg D, Sweeney J, Pettegrew J
Am J Psychiatry
. 1998 Jun;
155(6):774-8.
PMID: 9619149
Objective: Previous studies, mostly involving neuroleptic-treated patients, have suggested enlarged basal ganglia size in schizophrenia. The authors sought to examine basal ganglia volume in neuroleptic-naive psychotic patients. Method: Magnetic resonance...