J Terrig Thomas
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Explore the profile of J Terrig Thomas including associated specialties, affiliations and a list of published articles.
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10
Citations
273
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Recent Articles
1.
Thomas J, Dollins D, Andrykovich K, Chu T, Stultz B, Hursh D, et al.
Elife
. 2017 Mar;
6.
PMID: 28323621
The matricellular protein SMOC (Secreted Modular Calcium binding protein) is conserved phylogenetically from vertebrates to arthropods. We showed previously that SMOC inhibits bone morphogenetic protein (BMP) signaling downstream of its...
2.
Thomas J, Chhuy-Hy L, Andrykovich K, Moos Jr M
PLoS One
. 2016 Apr;
11(4):e0154294.
PMID: 27101391
In an attempt to identify the cell-associated protein(s) through which SMOC (Secreted Modular Calcium binding protein) induces mitogen-activated protein kinase (MAPK) signaling, the epidermal growth factor receptor (EGFR) became a...
3.
Thomas J, Schneider B, Frank E, Krizan S
Trends Biotechnol
. 2013 Nov;
31(12):665-7.
PMID: 24268060
No abstract available.
4.
Thomas J, Canelos P, Luyten F, Moos Jr M
J Biol Chem
. 2009 May;
284(28):18994-9005.
PMID: 19414592
The bone morphogenetic protein (BMP) family of signaling molecules and their antagonists are involved in patterning of the body axis and numerous aspects of organogenesis. Classical biochemical purification and protein...
5.
Wang W, Butler E, Veguilla V, Vassell R, Thomas J, Moos Jr M, et al.
J Virol Methods
. 2008 Aug;
153(2):111-9.
PMID: 18722473
Pseudotype reporter viruses provide a safe, quantitative, and high-throughput tool for assessing antibody neutralization for many viruses, including high pathogenicity H5 and H7 influenza A strains. However, adapting this system...
6.
Lories R, Peeters J, Bakker A, Tylzanowski P, Derese I, Schrooten J, et al.
Arthritis Rheum
. 2007 Dec;
56(12):4095-103.
PMID: 18050203
Objective: Ligands and antagonists of the WNT pathway are linked to osteoporosis and osteoarthritis. In particular, polymorphisms in the FRZB gene, a secreted WNT antagonist, have been associated with osteoarthritis....
7.
Thomas J, Prakash D, Weih K, Moos Jr M
J Biol Chem
. 2006 Jul;
281(36):26725-33.
PMID: 16829522
CDMP1/GDF5 has not demonstrated biological activity in Xenopus embryos when overexpressed by mRNA injection. We provide biological and biochemical evidence that to become active, the protein requires cleavage by two...
8.
Tylzanowski P, Bossuyt W, Thomas J, Luyten F
Genesis
. 2004 Dec;
40(4):200-4.
PMID: 15593330
The Wnt family of glycoproteins is involved in numerous developmental and disease processes in higher eukaryotes, exerting their action by binding to cell-surface receptors. In the extracellular space, Wnts are...
9.
Chambers D, Young D, Howard C, Thomas J, Boam D, Grant M, et al.
FEBS Lett
. 2002 Nov;
531(3):505-8.
PMID: 12435601
Type X collagen expression is restricted to hypertrophic chondrocytes in the endochondral growth plate. Transient transfection of reporter constructs containing the human collagen X promoter into primary growth plate chondrocytes...
10.
Everman D, Bartels C, Yang Y, Yanamandra N, Goodman F, Savarirayan R, et al.
Am J Med Genet
. 2002 Oct;
112(3):291-6.
PMID: 12357473
Growth/differentiation factor-5 (GDF5), also known as cartilage-derived morphogenetic protein-1 (CDMP-1), is a secreted signaling molecule that participates in skeletal morphogenesis. Heterozygous mutations in GDF5, which maps to human chromosome 20,...