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J T Alder

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Recent Articles
1.
Holmes C, McCulley M, Nicoll J, Alder J, Chen C, Francis P
Neurosci Lett . 2007 May; 420(1):58-60. PMID: 17481814
A common intronic single nucleotide polymorphism (T102C) in the 5-HT2A receptor gene is associated with the development of different neuropsychiatric symptoms, including hallucinations and depressive symptoms in Alzheimer's disease (AD)....
2.
Lai M, Tsang S, Alder J, Keene J, Hope T, Esiri M, et al.
Psychopharmacology (Berl) . 2004 Nov; 179(3):673-7. PMID: 15551121
Rationale: Previous studies have demonstrated reductions of serotonin 5-HT 2A receptors in the neocortex of Alzheimer's disease (AD) patients. However, it is unclear whether such losses play a role in...
3.
Chen C, Alder J, Bray L, Kingsbury A, Francis P, Foster O
Ann N Y Acad Sci . 1999 Feb; 861:288-9. PMID: 9928295
No abstract available.
4.
Harder J, MacLean C, Alder J, Francis P, Ridley R
Psychopharmacology (Berl) . 1996 Oct; 127(3):245-54. PMID: 8912403
Fornix transection in the marmoset produces a specific pattern of cognitive deficits, notably a lack of ability to recall visuospatial tasks learnt preoperatively, and a deficit in acquiring new visuospatial...
5.
Chen C, Alder J, Bowen D, Esiri M, McDonald B, Hope T, et al.
J Neurochem . 1996 Apr; 66(4):1592-8. PMID: 8627315
Presynaptic serotonergic markers, serotonin uptake sites, and concentrations of serotonin and 5-hydroxyindoleacetic acid were studied in the frontal and temporal cortex of 20 community-acquired cases of Alzheimer's disease and 16...
6.
Alder J, Chessell I, Bowen D
Neurochem Res . 1995 Jul; 20(7):769-71. PMID: 7477668
The proposal of cholinomimetic treatment as a rational basis for the therapy of Alzheimer's disease has been prematurely dismissed by some workers on the hypothesis of impaired coupling/signal transduction of...