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J S Symington

Explore the profile of J S Symington including associated specialties, affiliations and a list of published articles. Areas
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Articles 12
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1.
Song C, Tierney C, Loewenstein P, Pusztai R, Symington J, Tang Q, et al.
J Biol Chem . 1995 Oct; 270(40):23263-7. PMID: 7559479
The human adenovirus E1A 243R protein (243 residues) transcriptionally represses a set of cellular genes that regulate cellular growth and differentiation. We describe two lines of evidence that E1A repression...
2.
Parenti D, Symington J, Keiser J, Simon G
Clin Infect Dis . 1995 Oct; 21(4):1001-3. PMID: 8645786
In a retrospective review of microbiology records at the George Washington University Hospital from 1980 through 1990, Mycobacterium kansasii bacteremia was identified in 10 patients; this finding represented 4.5% of...
3.
Yu L, Zhang Z, Loewenstein P, Desai K, Tang Q, Mao D, et al.
J Virol . 1995 May; 69(5):3007-16. PMID: 7707527
The mechanism by which human immunodeficiency virus type 1 Tat transactivates the long terminal repeat promoter is not understood. It is generally believed that Tat has one or more transcription...
4.
Green M, Loewenstein P, Pusztai R, Symington J
Cell . 1988 Jun; 53(6):921-6. PMID: 2968158
We have shown previously that a synthetic peptide of 49 amino acids, encoding mainly adenovirus E1A protein domain 3 (PD3), functions as an autonomous transcriptional activator. Here we provide two...
5.
Lucher L, Brackmann K, Symington J, Green M
J Virol . 1986 May; 58(2):592-9. PMID: 2939260
The adenovirus E1A transforming region, which encodes immortalization, partial cell transformation, and gene activation functions, expresses two early mRNAs, 13S and 12S. Multiple-T antigen species with different electrophoretic mobilities are...
6.
Symington J, Lucher L, Brackmann K, Virtanen A, Pettersson U, Green M
J Virol . 1986 Mar; 57(3):848-56. PMID: 3005631
The i-leader is a 440-base-pair sequence located between 21.8 and 23.0 map units on the adenovirus type 2 genome and is spliced between the second and third segments of the...
7.
Lucher L, Symington J, Green M
J Virol . 1986 Mar; 57(3):839-47. PMID: 3005630
The adenovirus type 2 L1 region, which is located at 30.7 to 39.2 map units on the viral genome, is transcribed from the major late promoter during both early and...
8.
Kimelman D, Lucher L, Brackmann K, Symington J, Ptashne M, Green M
Proc Natl Acad Sci U S A . 1984 Oct; 81(20):6300-4. PMID: 6387701
Human adenovirus (Ad)-encoded early region 1A (E1A) tumor (T) antigens have been implicated in the positive regulation of viral early genes, the positive and negative regulation of some cellular genes,...
9.
Lucher L, Kimelman D, Symington J, Brackmann K, Cartas M, Thornton H, et al.
J Virol . 1984 Oct; 52(1):136-44. PMID: 6384554
A 16-amino acid peptide, H2N-Arg-Glu-Gln-Thr-Val-Pro-Val-Asp-Leu-Ser-Val-Lys-Arg-Pro-Arg-Cys-COOH (peptide 204), targeted to the common C-terminus of human adenovirus 12 (Ad12) tumor antigens encoded by the E1A 13S mRNA and 12S mRNA, has been...
10.
Lucher L, Brackmann K, Symington J, Green M
Virology . 1984 Jan; 132(1):217-21. PMID: 6559483
A peptide, H2N-Glu-Arg-Arg-Asn-Pro-Ser-Glu-Arg-Gly-Val-Pro-Ala-Gly-Phe-Ser-Gly-(Cys )COOH, containing the amino acid sequence at the NH2 terminus of the adenovirus type 2 (Ad2) E1B-coded large T antigen (E1B-53K) has been synthesized. Anti-peptide antibody was...