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J S Ralston

Explore the profile of J S Ralston including associated specialties, affiliations and a list of published articles. Areas
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Citations 40
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1.
De la Hoz D, Doctor B, Ralston J, Rush R, Wolfe A
Life Sci . 1986 Jul; 39(3):195-9. PMID: 3736320
A simple procedure has been developed for the large scale purification of fetal bovine serum acetylcholinesterase (AChE) (EC 3.1.1.7). The procedure involves two steps: batch adsorption of the AChE from...
2.
Rush R, Ralston J, Wolfe A
Biochem Pharmacol . 1985 Jun; 34(12):2063-8. PMID: 4004924
Aprophen, alpha-methyl-alpha-phenylbenzeneacetic acid-2-(diethylamino) ethyl ester, is a potent reversible inhibitor and a poor substrate of human serum butyrylcholinesterase (BuChE). Complex mixed competitive noncompetitive inhibition kinetics were observed; an apparent competitive...
3.
Ralston J, Rush R, Doctor B, Wolfe A
J Biol Chem . 1985 Apr; 260(7):4312-8. PMID: 3980478
Acetylcholinesterase (EC 3.1.1.7) from fetal bovine serum (FBS) was purified to electrophoretic homogeneity. The procedure involved procainamide affinity chromatography with native FBS, followed by chromatography on Sepharose 6B and DEAE-Sephadex....
4.
Ralston J, Main A, Kilpatrick B, CHASSON A
Biochem J . 1983 Apr; 211(1):243-50. PMID: 6870822
Two large-scale methods based primarily on the use of procainamide-Sepharose gels were developed for the purification of horse and human serum non-specific cholinesterases. With method I, the procainamide-Sepharose 4B gel...