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J S Beckman

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Articles 110
Citations 8381
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Recent Articles
1.
Mitton J, Linhart Y, Hamrick J, Beckman J
Theor Appl Genet . 2013 Dec; 51(1):5-13. PMID: 24317531
Variation of peroxidase enzymes is analyzed both in mature needle tissue and in open-pollinated seedling families of ponderosa pine, Pinus ponderosa, and is identified as being controlled by a single...
2.
Viera L, Ye Y, Beckman J
Methods Mol Med . 2011 Feb; 36:159-69. PMID: 21340972
Nitrotyrosine is an important marker for the formation of peroxynitrite and possibly other reactive nitrogen species derived from nitric oxide in vivo (1). Pathological conditions can substantially increase the production...
3.
Daiber A, Bachschmid M, Beckman J, Munzel T, Ullrich V
Biochem Biophys Res Commun . 2004 Apr; 317(3):873-81. PMID: 15081421
In a series of heme and non-heme proteins the nitration of tyrosine residues was assessed by complete pronase digestion and subsequent HPLC-based separation of 3-nitrotyrosine. Bolus addition of peroxynitrite caused...
4.
Martyshkin D, Mirov S, Zhuang Y, Crow J, Ermilov V, Beckman J
Spectrochim Acta A Mol Biomol Spectrosc . 2003 Oct; 59(13):3165-75. PMID: 14583292
A method has been developed for selective detection of the zinc-deficient form of Cu, Zn superoxide dismutase (SOD1) in vitro. Zinc-deficient SOD1 mutants have been implicated in the death of...
5.
Beckman J, Estevez A, Crow J, Barbeito L
Trends Neurosci . 2002 Mar; 24(11 Suppl):S15-20. PMID: 11881740
Amyotrophic lateral sclerosis (ALS) is a lethal disease that is characterized by the relentless death of motoneurons. Mutations to Cu-Zn superoxide dismutase (SOD), though occurring in just 2-3% of individuals...
6.
Dotan I, Ziv E, Dafni N, Beckman J, McCann R, Glover C, et al.
Biochem Biophys Res Commun . 2001 Oct; 288(3):603-9. PMID: 11676486
Protein kinase CK2 (formerly casein kinase II) is a highly conserved serine/threonine protein kinase ubiquitous in eukaryotic organisms. Previously, we have shown that CK2 is required for cell cycle progression...
7.
Beckman J
Circ Res . 2001 Aug; 89(4):295-7. PMID: 11509444
No abstract available.
8.
Sampson J, Beckman J
Arch Biochem Biophys . 2001 Jul; 392(1):8-13. PMID: 11469788
Mutations in Cu,Zn superoxide dismutase (Cu,Zn SOD) account for approximately 20% of cases of familial amyotrophic lateral sclerosis (ALS), a late-onset neurodegenerative disease affecting motor neurons. These mutations decrease protein...
9.
Xu J, Kim G, Chen S, Yan P, Ahmed S, Ku G, et al.
J Neurotrauma . 2001 Jun; 18(5):523-32. PMID: 11393255
Secondary tissue damage after spinal cord injury (SCI) may be due to inflammatory mediators. After SCI, the nuclear factor-kappaB (NF-kappaB) transcription factor can activate many pro-inflammatory genes, one of which...
10.
Zhang C, Reiter C, Eiserich J, Boersma B, Parks D, Beckman J, et al.
J Biol Chem . 2001 May; 276(29):27159-65. PMID: 11375389
The myeloperoxidase-derived oxidant hypochlorous acid (HOCl) is thought to contribute to endothelial dysfunction, but the mechanisms underlying this inhibitory effect are unknown. The present study tested the hypothesis that HOCl...