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J R Lancaster Jr

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Articles 66
Citations 2339
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Recent Articles
1.
Joshi M, Lancaster Jr J, Liu X, Ferguson Jr T
Nitric Oxide . 2001 Dec; 5(6):561-5. PMID: 11730363
A number of previous studies have indirectly (electron paramagnetic resonance, nitrite/nitrate, ribonuclease protection assay for inducible nitric oxide synthase (iNOS) mRNA, l-citrulline assay) demonstrated the production of nitrogen monoxide (NO)...
2.
Zhang Z, Oliver P, Lancaster Jr J, Schwarzenberger P, Joshi M, Cork J, et al.
FASEB J . 2001 Feb; 15(2):303-5. PMID: 11156944
Ectodomain shedding of cell surface membrane-anchoring proteins is an important process in a wide variety of physiological events(1, 2). Tumor necrosis factor alpha (TNF-alpha) converting enzyme (TACE) is the first...
3.
Zar H, Lancaster Jr J
Redox Rep . 2001 Jan; 5(5):303-10. PMID: 11145106
The ability of mild hypothermia (MH; 34 degrees C) to protect against postischemic endothelial injury and decrease reactive oxygen species' (ROS) formation was studied using lucigenin and luminol enhanced chemiluminescence...
4.
Thomas D, Liu X, Kantrow S, Lancaster Jr J
Proc Natl Acad Sci U S A . 2001 Jan; 98(1):355-60. PMID: 11134509
Endothelial nitric oxide (nitrogen monoxide) is synthesized at the intravascular/extravascular interface. We previously have reported the intravascular half-life of NO, as a result of consumption by erythrocytes, as approximately 2...
5.
Kantrow S, Gierman J, Jaligam V, Zhang P, Piantadosi C, Summer W, et al.
FEBS Lett . 2000 Oct; 483(2-3):119-24. PMID: 11042265
Cyclosporin (CsA) inhibits mitochondrial death signaling and opposes tumor necrosis factor (TNF)-induced apoptosis in vitro. However, CsA is also a potent inhibitor of calcineurin, a phosphatase that may participate in...
6.
Zhang Z, Kolls J, Oliver P, Good D, Schwarzenberger P, Joshi M, et al.
J Biol Chem . 2000 Apr; 275(21):15839-44. PMID: 10747938
Ectodomain shedding of cell surface proteins is an important process in a wide variety of physiological and developmental events. Recently, tumor necrosis factor-alpha-converting enzyme (TACE) has been found to play...
7.
Joshi M, Ponthier J, Lancaster Jr J
Free Radic Biol Med . 2000 Jan; 27(11-12):1357-66. PMID: 10641730
We describe a biphasic action of nitric oxide (NO) in its effects on oxidative killing of isolated cells: low concentrations protect against oxidative killing, while higher doses enhance killing, and...
8.
Tanigawa K, Bellomo R, Kellum J, Kim Y, Zar H, Lancaster Jr J, et al.
J Crit Care . 2000 Jan; 14(4):186-90. PMID: 10622753
Purpose: To investigate the role of nitric oxide (NO) in early endotoxemia on the systemic and regional blood flow by measuring the plasma nitrite/nitrate (NOx) and blood nitrosyl-hemoglobin (NO-Hb) levels....
9.
Zar H, Tanigawa K, Kim Y, Lancaster Jr J
Anesthesiology . 1999 Apr; 90(4):1103-11. PMID: 10201683
Background: Mild hypothermia, a promising therapy being evaluated for various clinical situations, may suppress the formation of reactive oxygen species during reperfusion and may ameliorate microcirculatory perfusion failure (the "no-reflow...
10.
Tanigawa K, Kim Y, Lancaster Jr J, Zar H
Crit Care Med . 1999 Mar; 27(2):401-6. PMID: 10075067
Objective: To test the hypothesis that fasting would aggravate postischemic lipid peroxidation in a perfused rat liver model. Design: Prospective, randomized study in a rat perfused liver model. Subjects: Male...