J P Simas
Overview
Explore the profile of J P Simas including associated specialties, affiliations and a list of published articles.
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Articles
13
Citations
591
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Recent Articles
1.
Stevenson P, Simas J, Efstathiou S
J Gen Virol
. 2009 Jul;
90(Pt 10):2317-2330.
PMID: 19605591
Many acute viral infections can be controlled by vaccination; however, vaccinating against persistent infections remains problematic. Herpesviruses are a classic example. Here, we discuss their immune control, particularly that of...
2.
Carlos T, Young D, Schneider M, Simas J, Randall R
J Gen Virol
. 2009 May;
90(Pt 9):2147-56.
PMID: 19458173
Although the replication cycle of parainfluenza virus type 5 (PIV5) is initially severely impaired in cells in an interferon (IFN)-induced antiviral state, the virus still targets STAT1 for degradation. As...
3.
Stevenson P, May J, Smith X, Marques S, Adler H, Koszinowski U, et al.
Nat Immunol
. 2002 Jul;
3(8):733-40.
PMID: 12101398
The murine gamma-herpesvirus-68 (MHV-68) K3 protein, like that of the Kaposi's sarcoma associated herpesvirus, down-regulates major histocompatibility complex (MHC) class I expression. However, how this contributes to viral replication in...
4.
Bridgeman A, Stevenson P, Simas J, Efstathiou S
J Exp Med
. 2001 Aug;
194(3):301-12.
PMID: 11489949
Herpesviruses encode a variety of proteins with the potential to disrupt chemokine signaling, and hence immune organization. However, little is known of how these might function in vivo. The B...
5.
Orge L, Simas J, Fernandes A, Ramos M, GALO A
Vet Rec
. 2000 Nov;
147(17):486-8.
PMID: 11093402
No abstract available.
6.
Donnelly C, Santos R, Ramos M, GALO A, Simas J
J Epidemiol Biostat
. 2000 Apr;
4(4):277-83.
PMID: 10764241
Background: Attention throughout Europe continues to focus on bovine spongiform encephalopathy (BSE), with increasing evidence linking it to the new variant of Creutzfeldt-Jakob disease in humans. In particular, recent attention...
7.
Parry C, Simas J, Smith V, Stewart C, Minson A, Efstathiou S, et al.
J Exp Med
. 2000 Feb;
191(3):573-8.
PMID: 10662803
Chemokines are a family of small proteins that interact with seven-transmembrane domain receptors and modulate the migration of immune cells into sites of inflammation and infection. The murine gammaherpesvirus 68...
8.
Simas J, Swann D, Bowden R, Efstathiou S
J Gen Virol
. 1999 Feb;
80 ( Pt 1):75-82.
PMID: 9934687
Murine gammaherpesvirus-68 (MHV-68) is a gamma2-herpesvirus that upon experimental infection of laboratory mice establishes a latent infection in B lymphocytes. To date, no virus-encoded gene products have been reported to...
9.
Simas J, Efstathiou S
Trends Microbiol
. 1998 Aug;
6(7):276-82.
PMID: 9717216
Murine gammaherpesvirus 68 (MHV-68) is a naturally occurring herpesvirus of wild rodents and is genetically related to human herpesvirus 8 and Epstein-Barr virus. The ability of MHV-68 to establish acute...
10.
Simas J, Bowden R, Paige V, Efstathiou S
J Gen Virol
. 1998 Feb;
79 ( Pt 1):149-53.
PMID: 9460936
Experimental infection of inbred strains of laboratory mice with murine herpesvirus 68 (MHV-68), a natural pathogen of wild rodents, results in acute productive infection of the lung followed by a...