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» Authors » J P Lenaerts

J P Lenaerts

Explore the profile of J P Lenaerts including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 27
Citations 594
Followers 0
Related Specialties
Allergy & Immunology
Biochemistry
General Medicine
Top 10 Co-Authors
J Van Damme
P Proost
R Conings
G Opdenakker
A Wuyts
W Put
S Struyf
A Billiau
P Menten
B Decock
Published In
J Immunol
Eur J Immunol
Eur J Biochem
Biochemistry
J Exp Med
Affiliations
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Recent Articles
1.
Gene cloning of a new plasma CC chemokine, activating and attracting myeloid cells in synergy with other chemoattractants
Struyf S, Stoops G, Van Coillie E, Gouwy M, Schutyser E, Lenaerts J, et al.
Biochemistry . 2001 Sep; 40(39):11715-22. PMID: 11570872
Chemokines are important mediators of cell migration during inflammation and normal leukocyte trafficking. Inflammatory chemokines are induced in multiple cell types at sites of infection. Here, we describe a novel...
2.
Diverging binding capacities of natural LD78beta isoforms of macrophage inflammatory protein-1alpha to the CC chemokine receptors 1, 3 and 5 affect their anti-HIV-1 activity and chemotactic potencies for neutrophils and eosinophils
Struyf S, Menten P, Lenaerts J, Put W, DHaese A, De Clercq E, et al.
Eur J Immunol . 2001 Jul; 31(7):2170-8. PMID: 11449371
Recently, the LD78beta isoform of the CC chemokine macrophage inflammatory protein (MIP)-1alpha was shown to efficiently chemoattract lymphocytes and monocytes and to inhibit infection of mononuclear cells by R5 HIV-1...
3.
Identification of a blood-derived chemoattractant for neutrophils and lymphocytes as a novel CC chemokine, Regakine-1
Struyf S, Proost P, Lenaerts J, Stoops G, Wuyts A, Van Damme J
Blood . 2001 Apr; 97(8):2197-204. PMID: 11290579
Chemokines constitute a large family of chemotactic cytokines that selectively attract different blood cell types. Although most inflammatory chemoattractants are only induced and released in the circulation during acute infection,...
4.
Regulated production and molecular diversity of human liver and activation-regulated chemokine/macrophage inflammatory protein-3 alpha from normal and transformed cells
Schutyser E, Struyf S, Menten P, Lenaerts J, Conings R, Put W, et al.
J Immunol . 2000 Oct; 165(8):4470-7. PMID: 11035086
Liver and activation-regulated chemokine (LARC), also designated macrophage inflammatory protein-3alpha (MIP-3alpha), Exodus, or CCL20, is a C-C chemokine that attracts immature dendritic cells and memory T lymphocytes, both expressing CCR6....
5.
NH2- and COOH-terminal truncations of murine granulocyte chemotactic protein-2 augment the in vitro and in vivo neutrophil chemotactic potency
Wuyts A, DHaese A, Cremers V, Menten P, Lenaerts J, De Loof A, et al.
J Immunol . 1999 Nov; 163(11):6155-63. PMID: 10570306
Chemokines are important mediators of leukocyte migration during the inflammatory response. Post-translational modifications affect the biological potency of chemokines. In addition to previously identified NH2-terminally truncated forms, COOH-terminally truncated forms...
6.
CD26/dipeptidyl-peptidase IV down-regulates the eosinophil chemotactic potency, but not the anti-HIV activity of human eotaxin by affecting its interaction with CC chemokine receptor 3
Struyf S, Proost P, Schols D, De Clercq E, Opdenakker G, Lenaerts J, et al.
J Immunol . 1999 Apr; 162(8):4903-9. PMID: 10202035
Chemokines attract and activate distinct sets of leukocytes. The CC chemokine eotaxin has been characterized as an important mediator in allergic reactions because it selectively attracts eosinophils, Th2 lymphocytes, and...
7.
Isolation of the CXC chemokines ENA-78, GRO alpha and GRO gamma from tumor cells and leukocytes reveals NH2-terminal heterogeneity. Functional comparison of different natural isoforms
Wuyts A, Govaerts C, Struyf S, Lenaerts J, Put W, Conings R, et al.
Eur J Biochem . 1999 Mar; 260(2):421-9. PMID: 10095777
Chemokines are a family of chemotactic peptides affecting leukocyte migration during the inflammatory response. Post-translational modification of chemokines has been shown to affect their biological potency. Here, the isolation and...
8.
Differential induction of monocyte chemotactic protein-3 in mononuclear leukocytes and fibroblasts by interferon-alpha/beta and interferon-gamma reveals MCP-3 heterogeneity
Menten P, Proost P, Struyf S, Van Coillie E, Put W, Lenaerts J, et al.
Eur J Immunol . 1999 Mar; 29(2):678-85. PMID: 10064085
Monocyte chemotactic protein-3 (MCP-3) is a pluripotent CC chemokine, attracting most leukocytic cell types. With the use of a sensitive and specific ELISA, MCP-3 was found to be inducible in...
9.
Processing by CD26/dipeptidyl-peptidase IV reduces the chemotactic and anti-HIV-1 activity of stromal-cell-derived factor-1alpha
Proost P, Struyf S, Schols D, Durinx C, Wuyts A, Lenaerts J, et al.
FEBS Lett . 1998 Aug; 432(1-2):73-6. PMID: 9710254
The chemokine stromal-cell-derived factor-1alpha (SDF-1alpha) chemoattracts lymphocytes and CD34+ haematopoietic progenitors and is the ligand for CXCR4 (CXC chemokine receptor 4), the main co-receptor for T-tropic HIV-1 strains. SDF-1alpha was...
10.
Differential usage of the CXC chemokine receptors 1 and 2 by interleukin-8, granulocyte chemotactic protein-2 and epithelial-cell-derived neutrophil attractant-78
Wuyts A, Proost P, Lenaerts J, Ben-Baruch A, Van Damme J, Wang J
Eur J Biochem . 1998 Aug; 255(1):67-73. PMID: 9692902
The inflammatory response is mediated by a family of chemotactic cytokines, designated chemokines. The receptor usage of the CXC chemokine granulocyte chemotactic protein-2 (GCP-2) was compared with that of interleukin-8...