J P Hendrick
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Explore the profile of J P Hendrick including associated specialties, affiliations and a list of published articles.
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22
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1570
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Recent Articles
1.
Barten D, Guss V, Corsa J, Loo A, Hansel S, Zheng M, et al.
J Pharmacol Exp Ther
. 2004 Sep;
312(2):635-43.
PMID: 15452193
gamma-Secretase inhibitors are one promising approach to the development of a therapeutic for Alzheimer's disease (AD). gamma-Secretase inhibitors reduce brain beta-amyloid peptide (Abeta), which is believed to be a major...
2.
Benjamin D, Robinson C, Hendrick J, Hartl F, Dobson C
Proc Natl Acad Sci U S A
. 1998 Jun;
95(13):7391-5.
PMID: 9636159
Nanoflow electrospray ionization has been used to introduce intact Escherichia coli ribosomes into the ion source of a mass spectrometer. Mass spectra of remarkable quality result from a partial, but...
3.
Ewalt K, Hendrick J, Houry W, Hartl F
Cell
. 1997 Aug;
90(3):491-500.
PMID: 9267029
The quantitative contribution of chaperonin GroEL to protein folding in E. coli was analyzed. A diverse set of newly synthesized polypeptides, predominantly between 10-55 kDa, interacts with GroEL, accounting for...
4.
Hendrick J, Hartl F
FASEB J
. 1995 Dec;
9(15):1559-69.
PMID: 8529835
Folding of newly synthesized polypeptides in the crowded cellular environment requires the assistance of so-called molecular chaperone proteins. Chaperones of the Hsp70 class and their partner proteins interact with nascent...
5.
Hendrick J, Langer T, Davis T, Hartl F, Wiedmann M
Proc Natl Acad Sci U S A
. 1993 Nov;
90(21):10216-20.
PMID: 8234279
Recent evidence supports the view that cellular protein folding may be mediated by molecular chaperones. A fundamental question concerns the stage in its biogenesis at which the folding protein makes...
6.
7.
Hendrick J, Wickner W
J Biol Chem
. 1991 Dec;
266(36):24596-600.
PMID: 1837025
Translocation of preproteins across the Escherichia coli inner membrane requires acidic phospholipids. We have studied the translocation of the precursor protein proOmpA across inverted inner membrane vesicles prepared from cells...
8.
Driessen A, Brundage L, Hendrick J, Schiebel E, Wickner W
Methods Cell Biol
. 1991 Jan;
34:147-65.
PMID: 1834920
No abstract available.
9.
Hartl F, Lecker S, Schiebel E, Hendrick J, Wickner W
Cell
. 1990 Oct;
63(2):269-79.
PMID: 2170023
The export of many E. coli proteins such as proOmpA requires the cytosolic chaperone SecB and the membrane-bound preprotein translocase. Translocase is a multisubunit enzyme with the SecA protein as...
10.
Brundage L, Hendrick J, Schiebel E, Driessen A, Wickner W
Cell
. 1990 Aug;
62(4):649-57.
PMID: 2167176
We have previously reconstituted the soluble phase of precursor protein translocation in vitro using purified proteins (the precursor proOmpA, the chaperone SecB, and the ATPase SecA) in addition to isolated...