J P Concordet
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Explore the profile of J P Concordet including associated specialties, affiliations and a list of published articles.
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20
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1828
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Recent Articles
1.
Bouleftour W, Juignet L, Verdiere L, Machuca-Gayet I, Thomas M, Laroche N, et al.
Bone
. 2018 Dec;
120:411-422.
PMID: 30529011
The two SIBLING (Small Integrin Binding Ligand N-linked Glycoproteins), bone sialoprotein (BSP) and osteopontin (OPN) are expressed in osteoblasts and osteoclasts. In mature BSP knockout (KO, ) mice, both bone...
2.
Charpentier M, Khedher A, Menoret S, Brion A, Lamribet K, Dardillac E, et al.
Nat Commun
. 2018 Mar;
9(1):1133.
PMID: 29556040
In genome editing with CRISPR-Cas9, transgene integration often remains challenging. Here, we present an approach for increasing the efficiency of transgene integration by homology-dependent repair (HDR). CtIP, a key protein...
3.
de Piedoue G, Andrieu-Soler C, Concordet J, Maurisse R, Sun J, Lopez B, et al.
Oligonucleotides
. 2007 Jul;
17(2):258-63.
PMID: 17638529
Single-stranded oligonucleotides (SSOs) mediate gene repair of punctual chromosomal mutations at a low frequency. We hypothesized that enhancement of DNA binding affinity of SSOs by intercalating agents may increase the...
4.
Schilling T, Concordet J, Ingham P
Dev Biol
. 1999 Jun;
210(2):277-87.
PMID: 10357891
Left-right (LR) asymmetry of the heart in vertebrates is regulated by early asymmetric signals in the embryo, including the secreted signal Sonic hedgehog (Shh), but less is known about LR...
5.
Lewis K, Concordet J, Ingham P
Dev Biol
. 1999 Mar;
208(1):14-29.
PMID: 10075838
Hedgehog signalling has been implicated in a variety of processes in vertebrate development, and in each case, the activity of Hh proteins is thought to be mediated by their interaction...
6.
Kroll M, Margottin F, Kohl A, Renard P, Durand H, Concordet J, et al.
J Biol Chem
. 1999 Mar;
274(12):7941-5.
PMID: 10075690
Activation of NF-kappaB transcription factors requires phosphorylation and ubiquitin-proteasome-dependent degradation of IkappaB proteins. We provide evidence that a human F-box protein, h-betaTrCP, a component of Skp1-Cullin-F-box protein (SCF) complexes, a...
7.
Hart M, Concordet J, Lassot I, Albert I, del los Santos R, Durand H, et al.
Curr Biol
. 1999 Mar;
9(4):207-10.
PMID: 10074433
Defects in beta-catenin regulation contribute to the neoplastic transformation of mammalian cells. Dysregulation of beta-catenin can result from missense mutations that affect critical sites of phosphorylation by glycogen synthase kinase...
8.
Spitz F, Demignon J, Porteu A, Kahn A, Concordet J, Daegelen D, et al.
Proc Natl Acad Sci U S A
. 1998 Nov;
95(24):14220-5.
PMID: 9826681
Myogenin, one of the MyoD family of proteins, is expressed early during somitogenesis and is required for myoblast fusion in vivo. Previous studies in transgenic mice have shown that a...
9.
Semenza G, Jiang B, Leung S, Passantino R, Concordet J, Maire P, et al.
J Biol Chem
. 1996 Dec;
271(51):32529-37.
PMID: 8955077
Hypoxia-inducible factor 1 (HIF-1) is a basic helix-loop-helix transcription factor which is expressed when mammalian cells are subjected to hypoxia and which activates transcription of genes encoding erythropoietin, vascular endothelial...
10.
Concordet J, Lewis K, Moore J, Goodrich L, Johnson R, Scott M, et al.
Development
. 1996 Sep;
122(9):2835-46.
PMID: 8787757
Signalling by members of the Hedgehog family of secreted proteins plays a central role in the development of vertebrate and invertebrate embryos. In Drosophila, transduction of the Hedgehog signal is...