J N Rodriguez-Lopez
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Explore the profile of J N Rodriguez-Lopez including associated specialties, affiliations and a list of published articles.
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61
Citations
747
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Recent Articles
1.
Pinero-Madrona A, Ruiz-Merino G, Cerezuela Fuentes P, Martinez-Barba E, Rodriguez-Lopez J, Cabezas-Herrera J
Clin Transl Oncol
. 2019 Feb;
21(10):1348-1356.
PMID: 30783917
Background: Recently, the quantification of mitoses in cutaneous melanoma has been discharged from the main prognostic variables of the TNM classification. Objective: To investigate the prognostic value of the presence...
2.
Montenegro M, Sanchez-Del-Campo L, Gonzalez-Guerrero R, Martinez-Barba E, Pinero-Madrona A, Cabezas-Herrera J, et al.
Oncogene
. 2016 May;
35(47):6143-6152.
PMID: 27132511
During the course of cancer progression, neoplastic cells undergo dynamic and reversible transitions between multiple phenotypic states, and this plasticity is enabled by underlying shifts in epigenetic regulation. Our results...
3.
Montenegro M, Gonzalez-Guerrero R, Sanchez-Del-Campo L, Pinero-Madrona A, Cabezas-Herrera J, Rodriguez-Lopez J
Cell Death Dis
. 2016 Apr;
7:e2180.
PMID: 27054335
Cancer is as much an epigenetic disease as it is a genetic disease, and epigenetic alterations in cancer often serve as potent surrogates for genetic mutations. Because the epigenetic factors...
4.
Montenegro M, Sanchez-Del-Campo L, Fernandez-Perez M, Saez-Ayala M, Cabezas-Herrera J, Rodriguez-Lopez J
Oncogene
. 2014 Jan;
34(2):135-43.
PMID: 24469033
Cancer is characterized by uncontrolled cell growth and the acquisition of metastatic properties. In most cases, the activation of oncogenes and/or deactivation of tumour suppressor genes lead to uncontrolled cell...
5.
Munoz-Munoz J, Acosta-Motos J, Garcia-Molina F, Varon R, Garcia-Ruiz P, Tudela J, et al.
Biochim Biophys Acta
. 2010 Mar;
1804(7):1467-75.
PMID: 20215052
Under aerobic or anaerobic conditions, tyrosinase undergoes a process of irreversible inactivation induced by its physiological substrate L-dopa. Under aerobic conditions, this inactivation occurs through a process of suicide inactivation...
6.
Garcia-Molina F, Munoz-Munoz J, Acosta J, Garcia-Ruiz P, Tudela J, Garcia-Canovas F, et al.
Biochim Biophys Acta
. 2009 Aug;
1794(12):1766-74.
PMID: 19695351
There is controversy in the literature concerning the action of tetrahydropterines on the enzyme tyrosinase and on melanogenesis in general. In this study, we demonstrate that tetrahydropterines can inhibit melanogenesis...
7.
Garcia-Molina F, Munoz-Munoz J, Garcia-Molina M, Molina-Alarcon M, Garcia-Ruiz P, Tudela J, et al.
J Agric Food Chem
. 2009 Jan;
57(4):1143-50.
PMID: 19170505
Captopril and mesna are molecules with a free thiol group, used as active ingredients due to their hypotensor and mucolytic properties, respectively. These compounds cross the hematoencephalic barrier and, due...
8.
Navarro-Peran E, Cabezas-Herrera J, Sanchez-Del-Campo L, Garcia-Canovas F, Rodriguez-Lopez J
Inflamm Res
. 2008 Oct;
57(10):472-8.
PMID: 18830563
Objective: To understand the mechanism by which (-)-epigallocatechin-3-gallate (EGCG), the major polyphenol of green tea, exerts its anti-inflammatory action. Methods: To check our hypothesis that the anti-inflammatory properties of EGCG...
9.
Munoz-Munoz J, Garcia-Molina F, Molina-Alarcon M, Tudela J, Garcia-Canovas F, Rodriguez-Lopez J
J Agric Food Chem
. 2008 Sep;
56(19):9215-24.
PMID: 18788750
The oxidation of green tea catechins by polyphenol oxidase/O2 and peroxidase/H2O2 gives rise to o-quinones and semiquinones, respectively, which inestability, until now, have hindered the kinetic characterization of enzymatic oxidation...
10.
Garcia-Molina F, Munoz J, Varon R, Rodriguez-Lopez J, Garcia-Canovas F, Tudela J
J Agric Food Chem
. 2007 Oct;
55(24):9739-49.
PMID: 17958393
Tyrosinase is a copper enzyme with broad substrate specifity toward a lot of phenols with different biotechnological applications. The availability of quick and reliable measurement methods of the enzymatic activity...