J N Octave
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Explore the profile of J N Octave including associated specialties, affiliations and a list of published articles.
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Recent Articles
1.
Ben Khalifa N, Tyteca D, Courtoy P, Renauld J, Constantinescu S, Octave J, et al.
Neurodegener Dis
. 2012 Feb;
10(1-4):92-5.
PMID: 22343802
Background: The two major isoforms of the human amyloid precursor protein (APP) are APP695 and APP751. They differ by the insertion of a Kunitz-type protease inhibitor (KPI) sequence in the...
2.
Octave J, De Sauvage F, Macq A, Maloteaux J, Laterre E
Neurochem Int
. 2010 May;
14(2):163-6.
PMID: 20504413
Neurofibrillary tangles and senile plaques, two neuropathological markers of Alzheimer's disease, may both contain peptide fragments derived from the ? amyloid protein. Human ? amyloid peptide precursor cDNAs have been...
3.
Octave J
Bull Mem Acad R Med Belg
. 2010 Mar;
164(7-9):181-6.
PMID: 20218187
Cellular metabolism of the amyloid precursor protein (APP) has been widely studied, but the function of the protein remains elusive. APP knock out mice do not show any phenotype, due...
4.
Octave J
Bull Mem Acad R Med Belg
. 2006 Jun;
160(10-12):445-9.
PMID: 16768248
A conclusive diagnosis of Alzheimer's disease (AD) can be made only by correlating clinical findings and neuropathological studies of post-mortem tissues. Two leading neuropathological changes correlate with the diagnosis of...
5.
Race V, Marie S, Kienlen-Campard P, Hermans E, Octave J, Van den Berghe G, et al.
Nucleosides Nucleotides Nucleic Acids
. 2004 Dec;
23(8-9):1227-9.
PMID: 15571234
Nucleotide concentrations were normal in adenylosuccinate lyase-deficient fibroblasts, and the succinylpurines were not toxic for cultured neuronal cells.
6.
Leroy K, Boutajangout A, Richardson J, Octave J, Lovestone S, Anderton B, et al.
Neurosci Lett
. 2003 Dec;
353(3):226-30.
PMID: 14665422
The expression of familial Alzheimer's disease mutants of presenilin-1 (PS1) proteins has been observed to induce cell death in cellular systems. To investigate how this phenomenon might be associated to...
7.
Brion J, Anderton B, Authelet M, Dayanandan R, Leroy K, Lovestone S, et al.
Biochem Soc Symp
. 2001 Jul;
(67):81-8.
PMID: 11447842
Neurofibrillary tangles (NFTs) are a characteristic neuropathological lesion of Alzheimer's disease (AD). They are composed of a highly-phosphorylated form of the microtubule-associated protein tau. We are investigating the relationship between...
8.
Festy F, Lins L, Peranzi G, Octave J, Brasseur R, Thomas A
Biochim Biophys Acta
. 2001 Apr;
1546(2):356-64.
PMID: 11295441
In a previous study, Hughes et al. [Proc. Natl. Acad. Sci. USA 93 (1996) 2065-2070] demonstrated that the amyloid peptide is able to interact with itself in a two-hybrid system...
9.
Toussaint O, Baret P, Brion J, Cras P, Collette F, De Deyn P, et al.
Exp Gerontol
. 2000 Dec;
35(8):901-16.
PMID: 11121679
No abstract available.
10.
Boyd A, Grosdent N, Totemeyer S, Geuijen C, Bleves S, Iriarte M, et al.
Eur J Cell Biol
. 2000 Nov;
79(10):659-71.
PMID: 11089914
Y. enterocolitica translocates virulence proteins, called Yop effectors, into the cytosol of eukaryotic cells. Here we investigated whether Y. enterocolitica could translocate Yops into a range of eukaryotic cells including...