J Matthew Kofron
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Explore the profile of J Matthew Kofron including associated specialties, affiliations and a list of published articles.
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10
Citations
256
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Recent Articles
1.
Rudman-Melnick V, Vanhoutte D, Stowers K, Sargent M, Adam M, Ma Q, et al.
Sci Rep
. 2024 Nov;
14(1):29307.
PMID: 39592775
Fibrosis is a common outcome of numerous pathologies, including chronic kidney disease (CKD), a progressive renal function deterioration. Current approaches to target activated fibroblasts, key effector contributors to fibrotic tissue...
2.
Rudman-Melnick V, Vanhoutte D, Stowers K, Sargent M, Adam M, Ma Q, et al.
Res Sq
. 2024 Aug;
PMID: 39184103
Fibrosis is a common outcome of numerous pathologies, including chronic kidney disease (CKD), a progressive renal function deterioration. Current approaches to target activated fibroblasts, key effector contributors to fibrotic tissue...
3.
Rudman-Melnick V, Vanhoutte D, Stowers K, Sargent M, Adam M, Ma Q, et al.
bioRxiv
. 2024 May;
PMID: 38798483
Fibrosis is a common outcome of numerous pathologies, including chronic kidney disease (CKD), a progressive renal function deterioration. Current approaches to target activated fibroblasts, key effector contributors to fibrotic tissue...
4.
Wu Q, Zhang J, Kumar S, Shen S, Kincaid M, Johnson C, et al.
Nature
. 2024 Mar;
627(8005):839-846.
PMID: 38509363
The bone marrow adjusts blood cell production to meet physiological demands in response to insults. The spatial organization of normal and stress responses are unknown owing to the lack of...
5.
Rudman-Melnick V, Adam M, Stowers K, Potter A, Ma Q, Chokshi S, et al.
Sci Rep
. 2024 Jan;
14(1):439.
PMID: 38172172
Examining kidney fibrosis is crucial for mechanistic understanding and developing targeted strategies against chronic kidney disease (CKD). Persistent fibroblast activation and tubular epithelial cell (TEC) injury are key CKD contributors....
6.
Rudman-Melnick V, Adam M, Stowers K, Potter A, Ma Q, Chokshi S, et al.
Res Sq
. 2023 Jun;
PMID: 37293022
Examining kidney fibrosis is crucial for mechanistic understanding and developing targeted strategies against chronic kidney disease (CKD). Persistent fibroblast activation and tubular epithelial cell (TEC) injury are key CKD contributors....
7.
Zhang J, Wu Q, Johnson C, Pham G, Kinder J, Olsson A, et al.
Nature
. 2021 Feb;
590(7846):457-462.
PMID: 33568812
In contrast to nearly all other tissues, the anatomy of cell differentiation in the bone marrow remains unknown. This is owing to a lack of strategies for examining myelopoiesis-the differentiation...
8.
Rudman-Melnick V, Adam M, Potter A, Chokshi S, Ma Q, Drake K, et al.
J Am Soc Nephrol
. 2020 Oct;
31(12):2793-2814.
PMID: 33115917
Background: Current management of AKI, a potentially fatal disorder that can also initiate or exacerbate CKD, is merely supportive. Therefore, deeper understanding of the molecular pathways perturbed in AKI is...
9.
Joshi R, Liu S, Brown M, Young S, Batie M, Kofron J, et al.
FASEB J
. 2015 Oct;
30(2):590-600.
PMID: 26443822
Lung stretch is critical for normal lung development and for compensatory lung growth after pneumonectomy (PNX), but the mechanisms by which strain induces matrix remodeling are unclear. Our prior work...
10.
Rao S, Chun C, Fan J, Kofron J, Yang M, Hegde R, et al.
Nature
. 2013 Jan;
494(7436):243-6.
PMID: 23334418
Vascular patterning is critical for organ function. In the eye, there is simultaneous regression of embryonic hyaloid vasculature (important to clear the optical path) and formation of the retinal vasculature...