J M Sands
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Explore the profile of J M Sands including associated specialties, affiliations and a list of published articles.
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84
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1242
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Recent Articles
1.
Lo E, Beckett L, Pan C, Robles D, Suga J, Sands J, et al.
Prostate Cancer Prostatic Dis
. 2015 Feb;
18(2):144-8.
PMID: 25667107
Background: Ketoconazole is a well-known CYP17-targeted systemic treatment for castration-resistant prostate cancer (CRPC). However, most of the published data has been in the pre-chemotherapy setting; its efficacy in the post-chemotherapy...
2.
Klein J, Kozlowski S, Antoun T, Sands J
J Membr Biol
. 2007 Feb;
212(2):139-44.
PMID: 17264983
In normal rats we showed that glucocorticoids participate in the downregulation of UT-A1 protein abundance in the inner medullary tip and in lowering of basal and vasopressin-stimulated facilitated urea permeability...
3.
Marini J, Klein J, Sands J, Van Amburgh M
J Anim Sci
. 2004 Apr;
82(4):1157-64.
PMID: 15080338
Urea recycling in ruminants has been studied extensively in the past, but the mechanisms regulating the amount of urea recycled or excreted remain obscure. To elucidate the role of urea...
4.
Sands J
J Membr Biol
. 2003 Feb;
191(3):149-63.
PMID: 12571750
Physiologic data provided evidence for specific urea transporter proteins in red blood cells and kidney inner medulla. During the past decade, molecular approaches resulted in the cloning of several urea...
5.
Ecelbarger C, Sands J, Doran J, Cacini W, Kishore B
Kidney Int
. 2001 Dec;
60(6):2274-82.
PMID: 11737600
Background: Cisplatin (CP) induced polyuria in rats is associated with a reduction in medullary hypertonicity, normally generated by the thick ascending limb (TAL) salt transporters, and the collecting duct urea...
6.
Timmer R, Klein J, Bagnasco S, Doran J, Verlander J, Gunn R, et al.
Am J Physiol Cell Physiol
. 2001 Sep;
281(4):C1318-25.
PMID: 11546670
A new polyclonal antibody to the human erythrocyte urea transporter UT-B detects a broad band between 45 and 65 kDa in human erythrocytes and between 37 and 51 kDa in...
7.
Bagnasco S, Peng T, Janech M, Karakashian A, Sands J
Am J Physiol Renal Physiol
. 2001 Aug;
281(3):F400-6.
PMID: 11502588
We have isolated and characterized the human homolog of the rat largest urea transporter of the UT-A family (hUT-A1). The 4.2-kb hUT-A1 cDNA encodes a 920-amino acid peptide, which is...
8.
DUCHESNE R, Klein J, Velotta J, Doran J, Rouillard P, Roberts B, et al.
Circ Res
. 2001 Jul;
89(2):139-45.
PMID: 11463720
Urea transporters have been cloned from kidney medulla (UT-A) and erythrocytes (UT-B). We determined whether UT-A proteins could be detected in heart and whether their abundance was altered by uremia...
9.
Bradford A, Terris J, Ecelbarger C, Klein J, Sands J, Chou C, et al.
Am J Physiol Renal Physiol
. 2001 Jun;
281(1):F133-43.
PMID: 11399654
UT-A1 is an extremely hydrophobic 929-amino acid integral membrane protein, expressed in the renal inner medullary collecting duct, with a central role in the urinary concentrating mechanism. Previous immunoblotting studies...
10.
Nakayama Y, Naruse M, Karakashian A, Peng T, Sands J, Bagnasco S
Biochim Biophys Acta
. 2001 Mar;
1518(1-2):19-26.
PMID: 11267655
We cloned the Slc14a2 gene and determined the genomic organization of the rat urea transporter UT-A. Slc14a2, the gene encoding the rat UT-A transporter, extends for more that 300 kb....