J M Reul
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Explore the profile of J M Reul including associated specialties, affiliations and a list of published articles.
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77
Citations
2338
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Recent Articles
1.
Preil J, Muller M, Gesing A, Reul J, Sillaber I, van Gaalen M, et al.
Endocrinology
. 2001 Oct;
142(11):4946-55.
PMID: 11606463
Recent investigations in mouse lines either deficient for the CRH receptor 1 (CRHR1) or 2 (CRHR2) suggest that the CRH neuronal system may comprise two separate pathways that can be...
2.
Stefferl A, Storch M, Linington C, Stadelmann C, Lassmann H, Pohl T, et al.
Endocrinology
. 2001 Jul;
142(8):3616-24.
PMID: 11459810
In this study, we demonstrate that disruption of neuroendocrine signaling is a major factor driving disease progression in myelin oligodendrocyte glycoprotein-induced chronic relapsing experimental autoimmune encephalomyelitis, an animal model of...
3.
Gesing A, Droste S, Linthorst A, Holsboer F, Reul J
J Neurosci
. 2001 Jun;
21(13):4822-9.
PMID: 11425909
We investigated whether acute stressors regulate functional properties of the hippocampal mineralocorticoid receptor (MR), which acts inhibitory on hypothalamic-pituitary-adrenocortical activity. Exposure of rats to forced swimming or novelty evoked a...
4.
Arzt E, Kovalovsky D, Igaz L, Costas M, Plazas P, Refojo D, et al.
Ann N Y Acad Sci
. 2001 Mar;
917:672-7.
PMID: 11268396
The main communicators between the neuroendocrine and immune systems are cytokines and hormones. We studied the molecular interaction between immune activators (cytokines and T-cell receptors [TCRs]) and the glucocorticoid receptor...
5.
Wiegers G, Stec I, Klinkert W, Linthorst A, Reul J
Neuroendocrinology
. 2001 Mar;
73(2):139-48.
PMID: 11244301
Glucocorticoids inhibit stimulus-induced T-cell proliferation, an early and essential parameter of cellular immunity. It was recently found however that physiological concentrations of glucocorticoids can also accelerate, not only inhibit, rat...
6.
Reul J, Droste S, Linthorst A, Holsboer F, Gesing A
Z Rheumatol
. 2001 Jan;
59 Suppl 2:II/22-5.
PMID: 11155799
Two types of corticosteroid receptors have been identified in the brain and pituitary that play an important role in the regulation of the hypothalamic-pituitary-adrenocortical (HPA) axis. These glucocorticoid hormone binding...
7.
Reul J, Gesing A, Droste S, Stec I, Weber A, Bachmann C, et al.
Eur J Pharmacol
. 2000 Oct;
405(1-3):235-49.
PMID: 11033331
Glucocorticoids exert their regulatory effects on the hypothalamic-pituitary-adrenocortical axis via two types of corticosteroid receptors: the glucocorticoid receptor and the mineralocorticoid receptor. Whereas the glucocorticoid receptor has a broad distribution...
8.
Steckler T, Holsboer F, Reul J
Baillieres Best Pract Res Clin Endocrinol Metab
. 2000 Jul;
13(4):597-614.
PMID: 10903817
Depression has been associated with impaired mineralocorticoid receptor function, restrained glucocorticoid receptor feedback at the level of the hypothalamic-pituitary-adrenal (HPA) axis, raised cortisol level and increased corticotropin-releasing factor activity, which...
9.
Wiegers G, Stec I, Klinkert W, Reul J
J Immunol
. 2000 Jun;
164(12):6213-20.
PMID: 10843673
CD4 serves as a coreceptor during Ag recognition by the TCR. This interaction results in a marked increase in the sensitivity of a T cell to Ag presented by MHC...
10.
Holter S, Linthorst A, Reul J, Spanagel R
Pharmacol Biochem Behav
. 2000 Jun;
66(1):143-51.
PMID: 10837854
Long-term voluntary alcohol drinking with repeated alcohol deprivation episodes has been suggested as animal model for some aspects of alcoholism. Using a radiotelemetric system, the present study investigated the occurrence...