J M Pawelek
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Explore the profile of J M Pawelek including associated specialties, affiliations and a list of published articles.
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Recent Articles
11.
Sodi S, Chakraborty A, Platt J, Kolesnikova N, Rosemblat S, Bolognia J, et al.
Pigment Cell Res
. 1999 Jan;
11(5):299-309.
PMID: 9877101
We recently reported that a majority of hybrids generated in vitro between weakly metastatic mouse Cloudman S91 melanoma cells and human or mouse macrophages showed enhanced metastatic potential. With few...
12.
Schallreuter K, Slominski A, Pawelek J, Jimbow K, Gilchrest B
Exp Dermatol
. 1998 Oct;
7(4):143-50.
PMID: 9758409
The pigments eumelanin and pheomelanin are the visually most striking products of specialized neural crest-derived cells (melanocytes), and provide color to both epidermis and hair shafts. While the intriguing and...
13.
Pawelek J, Low K, Bermudes D
Cancer Res
. 1997 Oct;
57(20):4537-44.
PMID: 9377566
There has been little investigation of bacteria as gene delivery vectors. Here, we demonstrate that genetically engineered Salmonella have many of the desirable properties of a delivery vector, including targeting...
14.
Chakraborty A, Funasaka Y, Slominski A, Ermak G, Hwang J, Pawelek J, et al.
Biochim Biophys Acta
. 1996 Aug;
1313(2):130-8.
PMID: 8781560
It is demonstrated that ultraviolet B (UVB) radiation stimulates increased expression of the proopiomelanocortin (POMC) gene which is accompanied by production and release of alpha-melanocyte stimulating hormone (alpha-MSH) and adrenocorticotropin...
15.
Chakraborty A, Platt J, Kim K, Kwon B, Bennett D, Pawelek J
Eur J Biochem
. 1996 Feb;
236(1):180-8.
PMID: 8617263
Recent advances in melanogenesis have focused on the role of dihydroxyindole-2-carboxylic acid[(HO)2IndCOOH]. For example, it has been shown that formation of (HO)2IndCOOH from dopachrome is catalyzed by dopachrome tautomerase, that...
16.
Bolognia J, Sodi S, Osber M, Pawelek J
Br J Dermatol
. 1995 Sep;
133(3):349-57.
PMID: 8546987
Glutathione (GSH) performs several important biological functions, including quenching of reactive oxygen species, and protection of cells from toxic compounds such as quinones. The first step in the synthesis of...
17.
Bolognia J, Sodi S, Chakraborty A, Fargnoli M, Pawelek J
Pigment Cell Res
. 1994 Oct;
7(5):320-5.
PMID: 7886005
Cultured mouse Cloudman melanoma cells, EMT6 breast carcinoma cells, and 3T3 fibroblasts all accumulated in the G2/M phase of the cell cycle when exposed to UVB radiation. The effects of...
18.
Orlow S, Zhou B, Chakraborty A, Drucker M, Pawelek J
J Invest Dermatol
. 1994 Aug;
103(2):196-201.
PMID: 8040609
Tyrosinase, tyrosinase-related protein-1 (TRP-1), and tyrosinase-related protein-2, (TRP-2, dopachrome tautomerase) were shown by immunoblotting and enzyme assays to copurify from extracts of Cloudman S91 melanoma cells. Antibodies to TRP-1 and...
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