J M Pawelek
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Explore the profile of J M Pawelek including associated specialties, affiliations and a list of published articles.
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50
Citations
970
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Recent Articles
1.
Bermudes D, Low B, Pawelek J
Methods Mol Med
. 2011 Mar;
35:419-36.
PMID: 21390821
Gene therapy approaches to cancer treatment have been limited by the ability of the delivery vectors to achieve specific high-level expression within tumor cells or the tumor environment following systemic...
2.
Chakraborty A, Pawelek J
Clin Exp Metastasis
. 2003 Jul;
20(4):365-73.
PMID: 12856724
GnT-V generated, beta1,6-branched polylactosamines are a common feature shared by normal granulocytes, monocytes, and a variety of malignant cells. Furthermore, activation of GnT-V in oncogenic transformation induces invasiveness and metastatic...
3.
Chakraborty A, de Freitas Sousa J, Espreafico E, Pawelek J
Gene
. 2001 Sep;
275(1):103-6.
PMID: 11574157
Artificial fusion of human monocyte with Cloudman S91 mouse melanoma cells resulted in hybrids that showed increased motility in vitro, enhanced metastatic potential in vivo, and also tended to be...
4.
Pawelek J
Pigment Cell Res
. 2001 Jul;
14(3):155-60.
PMID: 11434562
Increased public awareness of ultraviolet (UV) radiation-induced skin cancers has lead to new interest in technologies for protection from sun exposure. Although many sun protection formulations are available, few of...
5.
Pawelek J
Melanoma Res
. 2001 Feb;
10(6):507-14.
PMID: 11198471
This article reviews a long-standing hypothesis that metastases might be initiated through the generation of hybrids between primary tumour cells and tumour-infiltrating leucocytes such as macrophages. In this concept the...
6.
Chakraborty A, Funasaka Y, Slominski A, Bolognia J, Sodi S, Ichihashi M, et al.
Ann N Y Acad Sci
. 2000 May;
885:100-16.
PMID: 10816644
Ultraviolet B (UVB) radiation in the skin induces pigmentation that protects cells from further UVB damage and reduces photocarcinogenesis. Although the mechanisms are not well understood, our laboratory has shown...
7.
Chakraborty A, Sodi S, Rachkovsky M, Kolesnikova N, Platt J, Bolognia J, et al.
Cancer Res
. 2000 May;
60(9):2512-9.
PMID: 10811133
Cells from a lung metastasis, arising from Cloudman S91 melanoma cells implanted s.c. in the tail of a BALB/c nu/nu mouse, were comprised chiefly of host x tumor hybrids. These...
8.
Pawelek J, Chakraborty A, Rachkovsky M, Orlow S, Bolognia J, Sodi S
Cell Mol Biol (Noisy-le-grand)
. 2000 Jan;
45(7):1011-27.
PMID: 10644005
It was recently reported that a majority of hybrids generated in vitro between weakly metastatic mouse Cloudman S91 melanoma cells and human or mouse macrophages showed enhanced metastatic potential (Rachkovsky...
9.
Chakraborty A, Funasaka Y, Pawelek J, Nagahama M, Ito A, Ichihashi M
J Invest Dermatol
. 1999 Jun;
112(6):853-60.
PMID: 10383729
Immunohistochemical staining of human skin specimen showed the stronger localization of proopiomelanocortin peptides near the suprabasal layer of the epidermis, where keratinocytes are mostly differentiated. To test the possibilities of...
10.
Low K, Ittensohn M, Le T, Platt J, Sodi S, Amoss M, et al.
Nat Biotechnol
. 1999 Jan;
17(1):37-41.
PMID: 9920266
Systemically administered tumor-targeted Salmonella has been developed as an anticancer agent, although its use could be limited by the potential induction of tumor necrosis factor alpha (TNFalpha)-mediated septic shock stimulated...