J M McPherson
Overview
Explore the profile of J M McPherson including associated specialties, affiliations and a list of published articles.
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56
Citations
929
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Recent Articles
1.
McVie-Wylie A, Lee K, Qiu H, Jin X, Do H, Gotschall R, et al.
Mol Genet Metab
. 2008 Jun;
94(4):448-455.
PMID: 18538603
Pompe disease results in the accumulation of lysosomal glycogen in multiple tissues due to a deficiency of acid alpha-glucosidase (GAA). Enzyme replacement therapy for Pompe disease was recently approved in...
2.
Sumner D, Turner T, Cohen M, LoSavio P, Urban R, Nichols E, et al.
J Bone Miner Res
. 2003 Apr;
18(4):730-6.
PMID: 12674334
Controversy exists over the potency of bone healing in the aged skeleton, and there is concern that enhancement of bone regeneration after use of bone-stimulating growth factors may not be...
3.
Sumner D, Turner T, Urban R, Leven R, Hawkins M, Nichols E, et al.
J Orthop Res
. 2001 May;
19(1):85-94.
PMID: 11332625
The purposes of the present study were to determine if recombinant human transforming growth factor-beta-2 (rhTGF-beta2) enhances bone ingrowth into porous-coated implants and bone regeneration in gaps between the implant...
4.
Haudenschild D, McPherson J, Tubo R, Binette F
Anat Rec
. 2001 May;
263(1):91-8.
PMID: 11331975
Articular chondrocytes undergo a rapid change in phenotype and gene expression, termed dedifferentiation, when isolated from cartilage tissue and cultured on tissue culture plastic. On the other hand, "redifferentiation" of...
5.
Gagne T, Johnson J, McPherson J, Oldham C, Tubo R, Vaccaro C, et al.
J Orthop Res
. 2001 Feb;
18(6):882-90.
PMID: 11192247
Dedifferentiated human articular chondrocytes exhibited a wide variation in their capacity to proliferate and redifferentiate in an alginate suspension culture system. The greatest extent of proliferation and redifferentiation was seen...
6.
Friedman B, Vaddi K, Preston C, Mahon E, CATALDO J, McPherson J
Blood
. 1999 Apr;
93(9):2807-16.
PMID: 10216074
The objective of these studies was to characterize the macrophage mannose receptor binding and pharmacological properties of carbohydrate remodeled human placental-derived and recombinant beta-glucocerebrosidase (pGCR and rGCR, respectively). These are...
7.
Oxidation of methionine residues in antithrombin. Effects on biological activity and heparin binding
Van Patten S, Hanson E, Bernasconi R, Zhang K, Manavalan P, Cole E, et al.
J Biol Chem
. 1999 Apr;
274(15):10268-76.
PMID: 10187813
Commercially available human plasma-derived preparations of the serine protease inhibitor antithrombin (AT) were shown to contain low levels of oxidation, and we sought to determine whether oxidation might be a...
8.
Richards S, Garman R, Keyes L, Kavanagh B, McPherson J
Cell Immunol
. 1998 Jun;
184(2):85-91.
PMID: 9630834
Prolactin (PRL) is an immunomodulator that has been demonstrated to enhance immune responses both in vitro and in vivo. Prolactin enhances the proliferative response of lymphoid cells to both nonspecific...
9.
Edmunds T, Van Patten S, Pollock J, Hanson E, Bernasconi R, Higgins E, et al.
Blood
. 1998 Jun;
91(12):4561-71.
PMID: 9616152
Recombinant human antithrombin (rhAT) produced in transgenic goat milk was purified to greater than 99%. The specific activity of the rhAT was identical to human plasma-derived AT (phAT) in an...
10.
Binette F, McQuaid D, Haudenschild D, Yaeger P, McPherson J, Tubo R
J Orthop Res
. 1998 Jun;
16(2):207-16.
PMID: 9621895
Chondrocytes that were isolated from adult human articular cartilage changed phenotype during monolayer tissue culture, as characterized by a fibroblastic morphology and cellular proliferation. Increased proliferation was accompanied by downregulation...