J L Nichol
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Explore the profile of J L Nichol including associated specialties, affiliations and a list of published articles.
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27
Citations
379
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Recent Articles
1.
Gernsheimer T, George J, Aledort L, Tarantino M, Sunkara U, Matthew Guo D, et al.
J Thromb Haemost
. 2010 Mar;
8(6):1372-82.
PMID: 20230419
Background: Romiplostim is a peptibody protein that raises platelet counts during long-term treatment of patients with chronic immune thrombocytopenia (ITP). Clinical outcomes related to increased platelet counts include a reduced...
2.
Fureder W, Firbas U, Nichol J, Pistillo J, Winkler S, Hiesberger H, et al.
Lupus
. 2002 Jun;
11(4):221-6.
PMID: 12043885
Thrombocytopenia is a common phenomenon in patients suffering from systemic lupus erythematosus (SLE). The cause of thrombocytopenia in SLE, however, is poorly understood. In this study, 100 patients with SLE...
3.
Rice L, Nichol J, McMillan R, Roskos L, Bacile M
Am J Hematol
. 2002 Jan;
68(3):210-4.
PMID: 11754405
We report a patient with cyclic thrombocytopenia and antiplatelet antibodies, a variant of chronic immune thrombocytopenic purpura (ITP), with a several year history of periodic fluctuation of the platelet count,...
4.
Nichol J
Stem Cells
. 2000 Sep;
16 Suppl 2:165-75.
PMID: 11012188
The factor which is the primary regulator of megakaryocyte and platelet production has recently been identified as the ligand for the receptor Mpl. This discovery has resulted in substantial advances...
5.
Fabris F, Cordiano I, Steffan A, Ramon R, Scandellari R, Nichol J, et al.
Eur J Haematol
. 2000 Sep;
64(3):151-6.
PMID: 10997880
Chronic isolated hereditary macrothrombocytopenia (CHMT) is a congenital form of macrothrombocytopenia that seems to be due to defective production secondary to a disturbance in megakaryocyte fragmentation. To better understand the...
6.
Schmitt M, Gleiter C, Nichol J, Pralle L, Hasselblatt M, Poser W, et al.
Thromb Haemost
. 1999 Dec;
82(5):1422-7.
PMID: 10595631
Numerous reports exist on haematological pathology in alcoholism. However, no data are available regarding a potential involvement of haematopoietic growth factors in the recovery from alcohol-induced haematological abnormalities upon abstinence....
7.
Faraday N, Rade J, Johns D, Khetawat G, Noga S, DiPersio J, et al.
Blood
. 1999 Dec;
94(12):4084-92.
PMID: 10590053
Investigation of the molecular basis of megakaryocyte (MK) and platelet biology has been limited by an inadequate source of genetically manipulable cells exhibiting physiologic MK and platelet functions. We hypothesized...
8.
Ulich T, Del Castillo J, Senaldi G, Cheung E, Roskos L, Young J, et al.
Exp Hematol
. 1999 Jan;
27(1):117-30.
PMID: 9923450
A single injection of > or =10 microg/kg PEG-rHuMGDF in mice causes a dose-dependent increase in circulating platelets beginning on day 3 and peaking on days 5-6. The mean platelet...
9.
Griesshammer M, Hornkohl A, Nichol J, Hecht T, Raghavachar A, Heimpel H, et al.
Ann Hematol
. 1998 Dec;
77(5):211-5.
PMID: 9858146
Thrombopoietin (TPO) is the most important regulator of megakaryocyte development and platelet production. Platelet production is thought to be regulated by a negative regulatory feed back loop. In an attempt...
10.
Young G, Loechelt B, Rakusan T, Nichol J, Luban N
J Pediatr
. 1998 Dec;
133(6):765-9.
PMID: 9842041
Objectives: To determine the mechanism of human immunodeficiency virus (HIV)-associated thrombocytopenia by using thrombopoietin (TPO) levels. Study Design: TPO levels were measured in 14 HIV+ children with thrombocytopenia (TCP+), 28...