J L Magnenat
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Explore the profile of J L Magnenat including associated specialties, affiliations and a list of published articles.
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11
Citations
485
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Recent Articles
1.
Pugin J, Dunn I, Jolliet P, Tassaux D, Magnenat J, Nicod L, et al.
Am J Physiol
. 1998 Dec;
275(6):L1040-50.
PMID: 9843840
Positive-pressure mechanical ventilation supports gas exchange in patients with respiratory failure but is also responsible for significant lung injury. In this study, we have developed an in vitro model in...
2.
Ho Y, Magnenat J, Gargano M, Cao J
Environ Health Perspect
. 1998 Oct;
106 Suppl 5:1219-28.
PMID: 9788901
Reactive oxygen species (ROS) have been implicated in the pathogenesis of many clinical disorders such as adult respiratory distress syndrome, ischemia-reperfusion injury, atherosclerosis, neurodegenerative diseases, and cancer. Genetically engineered animal...
3.
Yoshida T, Maulik N, Engelman R, Ho Y, Magnenat J, Rousou J, et al.
Circulation
. 1997 Dec;
96(9 Suppl):II-216-20.
PMID: 9386101
Background: To test our hypothesis that intracellular antioxidant enzymes constitute a cellular defense against acute stress, we studied myocardial ischemia reperfusion injury in the setting of reduced level of glutathione...
4.
Ho Y, Magnenat J, Bronson R, Cao J, Gargano M, Sugawara M, et al.
J Biol Chem
. 1997 Jun;
272(26):16644-51.
PMID: 9195979
Glutathione peroxidase, a selenium-containing enzyme, is believed to protect cells from the toxicity of hydroperoxides. The physiological role of this enzyme has previously been implicated mainly using animals fed with...
5.
Reddy V, Lin L, Ho Y, Magnenat J, Ibaraki N, Giblin F, et al.
Ophthalmologica
. 1997 Jan;
211(3):192-200.
PMID: 9176901
Transgenic mice with elevated glutathione peroxidase (GSHPx) activity and gene knockout animals with a deficiency of the enzyme were used to investigate the role of GSHPx in defending the lens...
6.
Chen X, Stroun M, Magnenat J, Nicod L, Kurt A, Lyautey J, et al.
Nat Med
. 1996 Sep;
2(9):1033-5.
PMID: 8782463
Microsatellite instability is an important characteristic of many tumor types especially those associated with hereditary non-polyposis colorectal carcinoma (HNPCC) syndrome. Microsatellite alterations in 50% of primary small cell lung carcinoma...
7.
Spector A, Yang Y, Ho Y, Magnenat J, Wang R, Ma W, et al.
Exp Eye Res
. 1996 May;
62(5):521-40.
PMID: 8759521
This investigation examines the contribution of glutathione peroxidase (GSHPx-1) in degrading H2O2 in lens preparations. Rabbit (N/N1003A) and normal and GSHPx-1 transfected mouse (alpha TN4-1) lens epithelial cell lines and...
8.
Magnenat J, Nicod L, Auckenthaler R, Junod A
Am Rev Respir Dis
. 1991 Oct;
144(4):917-22.
PMID: 1928971
Bacterial pneumonia (BP) has recently been reported to be more frequent in human immunodeficiency virus (HIV)-infected patients than in normal hosts. This study reviews the clinical and radiologic manifestations of...
9.
Magnenat J, Junod A
Rev Mal Respir
. 1991 Jan;
8(1):95-9.
PMID: 2034861
We present five cases of episodic laryngeal dyskinesia. This term describes an entity associating acute dyspnea with inspiratory and/or expiratory stridor, sometimes ending in acute respiratory distress. The origin of...
10.
Jolliet P, Magnenat J, Kobel T, Chevrolet J
Chest
. 1990 Mar;
97(3):702-5.
PMID: 2306973
Tetanus is now rare in industrialized countries, occurring mainly in elderly patients. To assess whether aggressive therapy of these patients in the intensive care unit is justified, we retrospectively studied...