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J L Grogan

Explore the profile of J L Grogan including associated specialties, affiliations and a list of published articles. Areas
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Articles 18
Citations 731
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Recent Articles
1.
Yu X, Pappu R, Ramirez-Carrozzi V, Ota N, Caplazi P, Zhang J, et al.
Mucosal Immunol . 2013 Nov; 7(3):730-40. PMID: 24220298
Immune responses at mucosal barriers are regulated by innate type 2 lymphoid cells (ILC2s) that elaborate effector cytokines interleukins 5 and 13 (IL5 and IL13). IL25 and IL33 are key...
2.
Terry A, Grogan J, Casson D, Dalzell A, El-Matary W
Aliment Pharmacol Ther . 2011 Jun; 34(2):260-1. PMID: 21679212
No abstract available.
3.
Davies S, Grogan J, Blank R, Lim K, Locksley R, McKerrow J
Science . 2001 Nov; 294(5545):1358-61. PMID: 11701932
We have identified an alternate developmental pathway in the life cycle of the trematode pathogen Schistosoma mansoni. This pathway is used in immunodeficient hosts in which the parasite fails to...
4.
Grogan J, Mohrs M, Harmon B, Lacy D, Sedat J, Locksley R
Immunity . 2001 Apr; 14(3):205-15. PMID: 11290331
Naive CD4+ T cells activated through TCR/CD28 under Th1 or Th2 conditions expressed canonical cytokine patterns irrespective of cell division. Only cells that had divided fewer than four times were...
5.
Blackburn C, Grogan J, Augustine C, Miller J, Varigos G, Morahan G
Immunol Cell Biol . 2001 Mar; 79(2):128-31. PMID: 11264705
Transgenic mice were created in which a sheep keratin promoter directed the expression of IL-2 into the dermis. These KIL-2 transgenic mice were used to investigate the effects of localized...
6.
van den Biggelaar A, Grogan J, Filie Y, Jordens R, Kremsner P, Koning F, et al.
J Infect Dis . 2000 Jul; 182(1):260-5. PMID: 10882605
Chronic infection with helminths is associated with down-regulated antigen-specific T cell responses. In order to determine whether schistosome-specific T cells are present, yet functionally unresponsive, or absent in the periphery...
7.
Grogan J, Kramer A, Nogai A, Dong L, Ohde M, Schneider-Mergener J, et al.
J Immunol . 1999 Sep; 163(7):3764-70. PMID: 10490973
Activation of autoreactive T cells is a crucial event in the pathogenesis of autoimmune diseases. Cross-reactivity between microbial and self Ags (molecular mimicry) is one hypothesis that could explain the...
8.
Lohning M, Grogan J, Coyle A, Yazdanbakhsh M, Meisel C, Gutierrez-Ramos J, et al.
J Immunol . 1999 Apr; 162(7):3882-9. PMID: 10201906
Th cells are categorized into subsets based on the cytokine production of in vitro-differentiated Th populations. For in vivo-differentiated Th subsets, little is known about the heterogeneity of cytokine production...
9.
Grogan J, Kremsner P, Deelder A, Yazdanbakhsh M
Parasite Immunol . 1998 Aug; 20(7):345-9. PMID: 9717196
In this study we neutralized endogenous IL-10 in PBMC from individuals chronically infected with Schistosoma haematobium by using anti-IL-10 MoAbs, and examined the effect and adult worm antigen (AWA)-specific responses...
10.
Lohning M, Stroehmann A, Coyle A, Grogan J, Lin S, Gutierrez-Ramos J, et al.
Proc Natl Acad Sci U S A . 1998 Jun; 95(12):6930-5. PMID: 9618516
T helper (Th) cells can be categorized according to their cytokine expression. The differential induction of Th cells expressing Th1 and/or Th2 cytokines is key to the regulation of both...