J L Ebersole
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Explore the profile of J L Ebersole including associated specialties, affiliations and a list of published articles.
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240
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Recent Articles
1.
Gonzalez O, Kirakodu S, Ebersole J
Front Oral Health
. 2023 Dec;
4:1320083.
PMID: 38098978
Introduction: Periodontitis is delineated by a dysbiotic microbiome at sites of lesions accompanied by a dysregulated persistent inflammatory response that undermines the integrity of the periodontium. The interplay of the...
2.
Ebersole J, Kirakodu S, Nguyen L, Gonzalez O
J Periodontal Res
. 2023 Aug;
58(6):1171-1187.
PMID: 37638662
Objective: This report identified if gingival gene expression transcriptomes demonstrated unique profiles that discriminated periodontitis-susceptible (PDS) and periodontitis-resistant (PDR) animals in health and disease. Background: Nonhuman primates generally organize their...
3.
Gonzalez O, Kirakodu S, Nguyen L, Ebersole J
J Periodontal Res
. 2023 Aug;
58(6):1148-1170.
PMID: 37610132
Objective: This study examined the microbiome features specifically related to host macrophage polarization in health, initiation and progression of periodontitis, and in resolution samples using a nonhuman primate model of...
4.
Ebersole J, Kirakodu S, Nguyen L, Gonzalez O
J Dent Res
. 2023 May;
102(8):947-956.
PMID: 37232535
Many chronic inflammatory diseases demonstrate demographic associations such as sex, age, and race-ethnicity. Periodontitis has been found to be increased with age and in males. This study used nonhuman primates...
5.
Nguyen L, Chon J, Kim E, Cheng J, Ebersole J
JDR Clin Trans Res
. 2021 Feb;
7(2):145-153.
PMID: 33605165
Introduction: Periodontitis is a chronic inflammatory disease caused by multiple potential contributing factors such as bacterial biofilm infection of the tissues surrounding the teeth and environmental determinants and a dysregulated...
6.
Ebersole J, Kirakodu S, Orraca L, Gonzalez Martinez J, Gonzalez O
Clin Exp Immunol
. 2021 Feb;
204(3):373-395.
PMID: 33565609
Follicular helper T cells (Tfh) cells have been identified in the circulation and in tertiary lymphoid structures in chronic inflammation. Gingival tissues with periodontitis reflect chronic inflammation, so genomic footprints...
7.
Mejia F, Torgersen C, Berntsen E, Maroney J, Connor J, Fullerton A, et al.
Remote Sens (Basel)
. 2020 Aug;
12(9):1-1386.
PMID: 32850136
Dam operations can affect mixing of the water column thereby influencing thermal heterogeneity spatially and temporally. This occurs by restricting or eliminating connectivity in longitudinal, lateral, vertical and temporal dimensions....
8.
Ebersole J, Al-Sabbagh M, Dawson 3rd D
Immunol Lett
. 2019 Dec;
218:11-21.
PMID: 31863783
Aging humans display an increased prevalence and severity of periodontitis, although the mechanisms underlying these findings remain poorly understood. This report examined antigenic diversity of P. gingivalis related to disease...
9.
Ebersole J, Orraca L, Novak M, Kirakodu S, Gonzalez-Martinez J, Gonzalez O
Adv Exp Med Biol
. 2019 Nov;
1197:143-163.
PMID: 31732940
Epithelial cells and functions of the epithelium are critical to the health of the oral cavity. We used a nonhuman primate model to profile the transcriptome of gingival tissues in...
10.
Gonzalez O, Euzebio-Alves V, Alimova Y, Al-Attar A, Ebersole J
Adv Exp Med Biol
. 2019 Nov;
1197:79-95.
PMID: 31732936
Porphyromonas gingivalis is an oral pathogen with the ability to induce oral dysbiosis and periodontal disease. Nevertheless, the mechanisms by which P. gingivalis could abrogate the host-microbe symbiotic relationship leading...