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J L Corden

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11.
Okamoto H, Sheline C, Corden J, Jones K, Peterlin B
Proc Natl Acad Sci U S A . 1996 Oct; 93(21):11575-9. PMID: 8876177
Human immunodeficiency virus (HIV)-encoded trans-activator (Tat) acts through the trans-activation response element RNA stem-loop to increase greatly the processivity of RNA polymerase II. Without Tat, transcription originating from the HIV...
12.
Chiang C, Litingtung Y, Lee E, Young K, Corden J, Westphal H, et al.
Nature . 1996 Oct; 383(6599):407-13. PMID: 8837770
Targeted gene disruption in the mouse shows that the Sonic hedgehog (Shh) gene plays a critical role in patterning of vertebrate embryonic tissues, including the brain and spinal cord, the...
13.
Yuryev A, Patturajan M, Litingtung Y, Joshi R, Gentile C, GEBARA M, et al.
Proc Natl Acad Sci U S A . 1996 Jul; 93(14):6975-80. PMID: 8692929
Although transcription and pre-mRNA processing are colocalized in eukaryotic nuclei, molecules linking these processes have not previously been described. We have identified four novel rat proteins by their ability to...
14.
Yuryev A, Corden J
Genetics . 1996 Jun; 143(2):661-71. PMID: 8725217
The largest subunit of RNA polymerase II contains a repetitive C-terminal domain (CTD) consisting of tandem repeats of the consenus sequence Tyr1Ser2Pro3Thr4Ser5Pro6Ser7. Substitution of nonphosphorylatable amino acids at positions two...
15.
Meisels E, Gileadi O, Corden J
J Biol Chem . 1995 Dec; 270(52):31255-61. PMID: 8537392
The largest subunit of RNA polymerase II contains an essential carboxyl-terminal domain (CTD) that consists of highly conserved heptapeptide repeats with the consensus sequence Tyr-Ser-Pro-Thr-Ser-Pro-Ser. Yeast cells with a partially...
16.
West M, Corden J
Genetics . 1995 Aug; 140(4):1223-33. PMID: 7498765
The carboxyl-terminal domain (CTD) of the RNA polymerase II largest subunit plays an essential but poorly understood role in transcription. The CTD is highly phosphorylated in vivo and this modification...
17.
Gerber H, Hagmann M, Seipel K, Georgiev O, West M, Litingtung Y, et al.
Nature . 1995 Apr; 374(6523):660-2. PMID: 7715709
The RNA polymerase II carboxy-terminal domain (CTD) consists of tandem repeats of the sequence Tyr-Ser-Pro-Thr-Ser-Pro-Ser. The CTD may participate in activated transcription through interaction with a high-molecular-weight mediator complex. Such...
18.
Bartolomei M, Corden J
Mol Gen Genet . 1995 Mar; 246(6):778-82. PMID: 7898449
We report the identification of three new alpha-amanitin resistance mutations in the gene encoding the largest subunit of mouse RNA polymerase II (RPII215). These mutations are clustered in a region...
19.
Cagas P, Corden J
Proteins . 1995 Feb; 21(2):149-60. PMID: 7777490
The conformation of the repeating heptapeptide unit of the carboxyl-terminal domain of RNA Polymerase II, Y1S2P3T4S5P6S7 has been examined using nuclear magnetic resonance spectroscopy and circular dichroism. Nuclear Overhauser effects...
20.
Yuryev A, Corden J
Yeast . 1994 May; 10(5):659-62. PMID: 7941749
The nucleotide sequence of a Saccharomyces cerevisiae gene encoding a potential adenine phosphoribosyltransferase (APRT) has been determined. The protein encoded by this gene shows a high degree of similarity with...