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J K Wiencke

Explore the profile of J K Wiencke including associated specialties, affiliations and a list of published articles. Areas
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Articles 96
Citations 1611
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Recent Articles
1.
Wiencke J, Nissen E, Koestler D, Tamaki S, Tamaki C, Hansen H, et al.
Res Sq . 2024 Jan; PMID: 38234734
Glioblastomas (GBM) are lethal central nervous system cancers associated with tumor and systemic immunosuppression. Heterogeneous monocyte myeloid-derived suppressor cells (M-MDSC) are implicated in the altered immune response in GBM, but...
2.
Wiencke J, Molinaro A, Warrier G, Rice T, Clarke J, Taylor J, et al.
Nat Commun . 2022 Sep; 13(1):5505. PMID: 36127421
Assessing individual responses to glucocorticoid drug therapies that compromise immune status and affect survival outcomes in neuro-oncology is a great challenge. Here we introduce a blood-based neutrophil dexamethasone methylation index...
3.
Ishibe N, Wiencke J, Zuo Z, McMillan A, Spitz M, Kelsey K
Biomarkers . 2013 Aug; 3(3):219-26. PMID: 23899331
One of the most consistently observed exposure-disease relationship is the one between cigarette smoking and lung cancer. Aromatic amines and their metabolites are found in tobacco smoke and may be...
4.
Walsh K, Chokkalingam A, Hsu L, Metayer C, de Smith A, Jacobs D, et al.
Leukemia . 2013 Apr; 27(12):2416-9. PMID: 23615557
No abstract available.
5.
Nelson H, Christensen B, Plaza S, Wiencke J, Marsit C, Kelsey K
Lung Cancer . 2009 Oct; 69(1):51-3. PMID: 19854534
The let-7 family of microRNAs are important regulatory molecules in lung cancer. One downstream target of let-7 is the RAS gene family, including KRAS, an important oncogene in the etiology...
6.
Wiencke J, Zheng S, Morrison Z, Yeh R
Oncogene . 2007 Oct; 27(17):2412-21. PMID: 17968314
Histone H3 lysine 9 trimethylation (H3K9Me3) has been associated with transcriptional repression, but recent findings implicate this chromatin modification in transcriptional activation and mRNA elongation by RNA polymerase II. Here,...
7.
McClean M, Wiencke J, Kelsey K, Varkonyi A, Ngo L, Eisen E, et al.
Ann Occup Hyg . 2006 Oct; 51(1):27-34. PMID: 17046959
Objective: Asphalt is used extensively in the highway construction industry and contains a complex mixture of polycyclic aromatic hydrocarbons, some of which are known or suspected to be human carcinogens....
8.
Kraunz K, Nelson H, Liu M, Wiencke J, Kelsey K
Br J Cancer . 2005 Sep; 93(8):949-52. PMID: 16175182
Bone morphogenetic proteins (BMPs) are an integral component of the TGFbeta superfamily, responsible for regulation of cell proliferation, differentiation, migration and programmed cell death in a variety of cell types....
9.
Wiemels J, Zhang Y, Chang J, Zheng S, Metayer C, Zhang L, et al.
Leukemia . 2005 Jan; 19(3):415-9. PMID: 15674422
We explored the relationship of RAS gene mutations with epidemiologic and cytogenetic factors in a case series of children with leukemia. Diagnostic bone marrow samples from 191 incident leukemia cases...
10.
McClean M, Rinehart R, Ngo L, Eisen E, Kelsey K, Wiencke J, et al.
Ann Occup Hyg . 2004 Aug; 48(6):565-78. PMID: 15292037
Objectives: Using urinary 1-hydroxypyrene (1-OHP) as a measure of total absorbed dose, the primary objective of this study was to evaluate the total effect of inhalation and dermal PAH exposures...