J Justin Milner
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Explore the profile of J Justin Milner including associated specialties, affiliations and a list of published articles.
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2540
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Recent Articles
1.
Cheng M, Chu A, Li Z, Yang S, Smith M, Zhang Q, et al.
JCI Insight
. 2024 Oct;
9(22).
PMID: 39388288
Immune evasion by tumors is promoted by low T cell infiltration, ineffective T cell activity directed against the tumor, and reduced tumor antigen presentation. The TET2 DNA dioxygenase gene is...
2.
Zhou X, Wang Y, Dou Z, Delfanti G, Tsahouridis O, Pellegry C, et al.
Nat Cancer
. 2024 Oct;
5(11):1607-1621.
PMID: 39354225
Human natural killer T (NKT) cells have been proposed as a promising cell platform for chimeric antigen receptor (CAR) therapy in solid tumors. Here we generated murine CAR-NKT cells and...
3.
Ulibarri M, Lin Y, Ramprashad J, Han G, Hasan M, Mithila F, et al.
Cell Rep
. 2024 Aug;
43(8):114621.
PMID: 39153200
Resident memory T cells (TRMs) play a vital role in regional immune defense. Although laboratory rodents have been extensively used to study fundamental TRM biology, poor isolation efficiency and low...
4.
Ranek J, Stallaert W, Milner J, Redick M, Wolff S, Beltran A, et al.
Nat Commun
. 2024 Mar;
15(1):2765.
PMID: 38553455
Single-cell technologies can measure the expression of thousands of molecular features in individual cells undergoing dynamic biological processes. While examining cells along a computationally-ordered pseudotime trajectory can reveal how changes...
5.
Ulibarri M, Lin Y, Ramprashad J, Han G, Hasan M, Mithila F, et al.
bioRxiv
. 2023 Dec;
PMID: 38076957
Resident Memory T cells (TRM) play a vital role in regional immune defense in barrier organs. Although laboratory rodents have been extensively used to study fundamental TRM biology, poor isolation...
6.
Alvarez-Breckenridge C, Anderson K, Correia A, Demehri S, Dinh H, Dixon K, et al.
Cancer Immunol Res
. 2023 Oct;
11(12):1571-1577.
PMID: 37906619
The Arthur and Sandra Irving Cancer Immunology Symposium has been created as a platform for established cancer immunologists to mentor trainees and young investigators as they launch their research career...
7.
Reina-Campos M, Heeg M, Kennewick K, Mathews I, Galletti G, Luna V, et al.
Nature
. 2023 Aug;
621(7977):179-187.
PMID: 37648857
Tissue resident memory CD8 T (T) cells offer rapid and long-term protection at sites of reinfection. Tumour-infiltrating lymphocytes with characteristics of T cells maintain enhanced effector functions, predict responses to...
8.
Pratt B, Milner J
Science
. 2023 Jun;
380(6649):1011-1012.
PMID: 37289885
T cells primed in the gut influence immune responses to extraintestinal tumors.
9.
Nguyen Q, Takehara K, Deng T, OShea S, Heeg M, Omilusik K, et al.
Sci Immunol
. 2023 May;
8(83):eabq7486.
PMID: 37172104
After resolution of infection, T cells differentiate into long-lived memory cells that recirculate through secondary lymphoid organs or establish residence in tissues. In contrast to CD8 tissue-resident memory T cells...
10.
Quon S, Yu B, Russ B, Tsyganov K, Nguyen H, Toma C, et al.
Immunity
. 2023 Apr;
56(5):959-978.e10.
PMID: 37040762
Although the importance of genome organization for transcriptional regulation of cell-fate decisions and function is clear, the changes in chromatin architecture and how these impact effector and memory CD8 T ...