J J Owen
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Explore the profile of J J Owen including associated specialties, affiliations and a list of published articles.
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129
Citations
2124
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Recent Articles
1.
Owen J, Perry L, Delaney R, Charig M, Smith M, Hart L
Thorax
. 2008 Mar;
63(4):359, 376.
PMID: 18364445
No abstract available.
2.
Hodges P, Carrico P, Hogan J, ONeill K, Owen J, Mangan M, et al.
Nucleic Acids Res
. 2001 Dec;
30(1):137-41.
PMID: 11752275
The Proteome Division of Incyte Genomics has released new volumes to the BioKnowledge Library to add human, mouse and rat protein information to its rich collection of model organism Proteome...
3.
Revest J, Suniara R, Kerr K, Owen J, Dickson C
J Immunol
. 2001 Aug;
167(4):1954-61.
PMID: 11489975
Mice deficient for fibroblast growth factor (Fgf)R2-IIIb show a block in thymic growth after embryonic day 12.5, a stage that just precedes its detection in thymic epithelial cells. Fgf7 and...
4.
Owen J, McLoughlin D, Suniara R, Jenkinson E
Curr Top Microbiol Immunol
. 2000 Oct;
251:133-7.
PMID: 11036768
We have reviewed the evidence that thymic mesenchymal cells and their progeny thymic fibroblasts play an important role in early T-cell development. Although it is possible that mesenchyme plays an...
5.
Suniara R, Jenkinson E, Owen J
J Exp Med
. 2000 Mar;
191(6):1051-6.
PMID: 10727466
We show that the mesenchymal cells that surround the 12-d mouse embryo thymus are necessary for T cell differentiation. Thus, epithelial lobes with attached mesenchyme generate all T cell populations...
6.
Jenkinson E, Parnell S, Shuttleworth J, Owen J, Anderson G
J Immunol
. 1999 Nov;
163(11):5781-5.
PMID: 10570260
Thymic epithelial cells are uniquely efficient in mediating positive selection, suggesting that in addition to providing peptide/MHC complexes for TCR ligation, they may also provide additional support for this process....
7.
Owen J, McLoughlin D, Suniara R, Jenkinson E
Braz J Med Biol Res
. 1999 Jul;
32(5):551-5.
PMID: 10412566
The thymus contains an extensive extracellular matrix. Although thymocytes express integrins capable of binding to matrix molecules, the functional significance of the matrix for T cell development is uncertain. We...
8.
Wilkinson B, Owen J, Jenkinson E
J Immunol
. 1999 Apr;
162(7):3873-81.
PMID: 10201905
Colonization of the thymic rudiment during development is initiated before vascularization so that hemopoietic precursors must leave the pharyngeal vessels and migrate through the perithymic mesenchyme to reach the thymus,...
9.
Suniara R, Jenkinson E, Owen J
Eur J Immunol
. 1999 Feb;
29(1):75-80.
PMID: 9933088
Stem cells first enter the thymus around the 11th to 12th days of gestation in BALB/c mouse embryos. The phenotype of these stem cells has been difficult to determine because...
10.
Anderson K, Moore N, McLoughlin D, Jenkinson E, Owen J
Dev Comp Immunol
. 1998 Aug;
22(3):367-77.
PMID: 9700465
Thymic epithelial cells are unique in their ability to support positive selection and are essential throughout thymocyte development. Here, we describe a technique for measuring the proliferation of thymic epithelial...