J J Ludtke
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Explore the profile of J J Ludtke including associated specialties, affiliations and a list of published articles.
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Articles
7
Citations
299
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0
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Recent Articles
1.
Specific recognition of protein carboxy-terminal sequences by natural IgM antibodies in normal serum
Sokoloff A, Bock I, Zhang G, Hoffman S, Dama J, Ludtke J, et al.
Mol Ther
. 2001 Jun;
3(6):821-30.
PMID: 11407895
Our previous study indicated that normal serum contains complement-fixing natural IgM antibodies reacting with a large variety of randomly generated protein carboxy-termini. Here we show that the "carboxy-terminal" IgM (C-IgM)...
2.
Ludtke J, Zhang G, Sebestyen M, Wolff J
J Cell Sci
. 1999 May;
112 ( Pt 12):2033-41.
PMID: 10341220
Although the entry of DNA into the nucleus is a crucial step of non-viral gene delivery, fundamental features of this transport process have remained unexplored. This study analyzed the effect...
3.
Sebestyen M, Ludtke J, Bassik M, Zhang G, Budker V, Lukhtanov E, et al.
Nat Biotechnol
. 1998 Feb;
16(1):80-5.
PMID: 9447599
The nuclear entry of exogenous DNA in mammalian cells is critical for efficient gene transfer. A novel technique was developed for the covalent attachment of cationic peptides to double-stranded DNA...
4.
Hagstrom J, Ludtke J, Bassik M, Sebestyen M, Adam S, Wolff J
J Cell Sci
. 1997 Oct;
110 ( Pt 18):2323-31.
PMID: 9378781
DNA can enter intact mammalian nuclei with varying degrees of efficiency in both transfected and microinjected cells, yet very little is known about the mechanism by which it crosses the...
5.
Hagstrom J, Sebestyen M, Budker V, Ludtke J, Fritz J, Wolff J
Biochim Biophys Acta
. 1996 Oct;
1284(1):47-55.
PMID: 8865814
Transfection competent complexes were assembled using a three component system. The constituents of the basic system were plasmid DNA, cationic DNA binding protein (NLS-H1) and anionic liposomes (dioleoyl phosphatidylethanolamine (DOPE)...
6.
Wolff J, Dowty M, Jiao S, Repetto G, Berg R, Ludtke J, et al.
J Cell Sci
. 1992 Dec;
103 ( Pt 4):1249-59.
PMID: 1487500
Plasmid DNA or artificial mRNA injected intramuscularly into skeletal muscle via a 27 g needle expressed transgenes at relatively efficient levels in skeletal myofibers and cardiac cells. In the present...
7.
Wolff J, Ludtke J, Acsadi G, Williams P, Jani A
Hum Mol Genet
. 1992 Sep;
1(6):363-9.
PMID: 1301910
Plasmid pRSVL persisted and expressed luciferase for at least 19 months in mouse skeletal muscle after intramuscular injection. Other injected plasmids also stably expressed long-term suggesting that any plasmid DNA...