J J Leary
Overview
Explore the profile of J J Leary including associated specialties, affiliations and a list of published articles.
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Articles
22
Citations
711
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0
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Recent Articles
1.
Frew N, Leary J, Isenhour T
Anal Chem
. 2012 Feb;
44(4):665-71.
PMID: 22309520
No abstract available.
2.
Sarisky R, Bartus H, Dennis S, Quail M, Nguyen T, Wittrock R, et al.
BMC Infect Dis
. 2001 Dec;
1:24.
PMID: 11749671
Background: Acyclovir (ACV) resistant herpes simplex virus (HSV) isolates can be readily selected in animal infection models receiving suboptimal ACV treatment, however no comparative studies of the emergence of resistance...
3.
Levin M, Weinberg A, Leary J, Sarisky R
Pediatr Infect Dis J
. 2001 Dec;
20(11):1094-7.
PMID: 11734722
Genotypic analysis of herpes simplex virus (HSV) DNA extracted from clinical specimens from a case of fatal disseminated neonatal HSV demonstrated that an infant developed an acyclovir-resistant HSV containing a...
4.
Sarisky R, Cano R, Nguyen T, Wittrock R, Duffy K, Clark P, et al.
Clin Infect Dis
. 2001 Nov;
33(12):2034-9.
PMID: 11712095
In vitro susceptibility assays of herpes simplex virus (HSV) do not necessarily correlate with treatment outcome. An HSV type 1 (HSV-1) isolate, N4, recovered from a patient who presented with...
5.
Shin Y, Cai G, Weinberg A, Leary J, Levin M
J Clin Microbiol
. 2001 Mar;
39(3):913-7.
PMID: 11230403
The proportion of acyclovir (ACV)-resistant herpes simplex virus (HSV) isolates in clinical specimens and laboratory isolates was determined. HSV isolates in clinical specimens and laboratory isolates were cultured in the...
6.
Sarisky R, Quail M, Clark P, Nguyen T, Halsey W, Wittrock R, et al.
J Virol
. 2001 Feb;
75(4):1761-9.
PMID: 11160674
Penciclovir (PCV), an antiherpesvirus agent in the same class as acyclovir (ACV), is phosphorylated in herpes simplex virus (HSV)-infected cells by the viral thymidine kinase (TK). Resistance to ACV has...
7.
Lipsitch M, Bacon T, Leary J, Antia R, Levin B
Antimicrob Agents Chemother
. 2000 Sep;
44(10):2824-35.
PMID: 10991866
Herpes simplex virus type 1 (HSV-1) causes recurrent herpes labialis (RHL), a common disease afflicting up to 40% of adults worldwide. Mathematical models are used to analyze the effect of...
8.
Sarisky R, Nguyen T, Duffy K, Wittrock R, Leary J
Antimicrob Agents Chemother
. 2000 May;
44(6):1524-9.
PMID: 10817703
Spontaneous mutations within the herpes simplex virus (HSV) genome are introduced by errors during DNA replication. Indicative of the inherent mutation rate of HSV DNA replication, heterogeneous HSV populations containing...
9.
Tal-Singer R, Podrzucki W, Lasner T, Skokotas A, Leary J, Fraser N, et al.
J Virol
. 1998 Jan;
72(2):1252-61.
PMID: 9445025
The detailed mechanism which governs the choice between herpes simplex virus (HSV) latency and reactivation remains to be elucidated. It is probable that altered expression of cellular factors in sensory...
10.
Tal-Singer R, Lasner T, Podrzucki W, Skokotas A, Leary J, Berger S, et al.
J Virol
. 1997 Jul;
71(7):5268-76.
PMID: 9188595
Herpes simplex virus (HSV) replicates in peripheral tissues and forms latent infections in neurons of the peripheral nervous system. It can be reactivated from latency by various stimuli to cause...