J J Kastelein
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Explore the profile of J J Kastelein including associated specialties, affiliations and a list of published articles.
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Articles
157
Citations
2431
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Recent Articles
1.
Van Dam M, Stalenhoef A, Wittekoek J, Trip M, Prins M, Kastelein J
Clin Drug Investig
. 2016 Aug;
21(3):175-81.
PMID: 27517547
Objectives: To compare the effects of concentrated n-3 fatty acids (Omacor™) and gemfibrozil in patients with severe hypertriglyceridaemia. The primary objective was to measure the change in serum triglyceride (TG),...
2.
Smilde T, Trip M, Wollersheim H, van Wissen S, Kastelein J, Stalenhoef A
Clin Drug Investig
. 2013 Jan;
20(2):67-79.
PMID: 23315348
Objective: Hypercholesterolaemia is strongly associated with increased vessel wall thickness as measured by ultrasound. The question is whether aggressive cholesterol lowering with high-dose atorvastatin can alter intima media thickening to...
3.
van Leuven S, Birjmohun R, Franssen R, Bisoendial R, De Kort H, Levels J, et al.
J Thromb Haemost
. 2008 Nov;
7(2):347-54.
PMID: 18983488
Background: High-density lipoprotein (HDL) exerts a variety of anti-atherothrombotic functions, including a potent anti-inflammatory impact. In line, the direct pro-inflammatory effects of C-reactive protein (CRP) can be attenuated by HDL...
4.
van Leuven S, Franssen R, Kastelein J, Levi M, Stroes E, Tak P
Rheumatology (Oxford)
. 2007 Aug;
47(1):3-7.
PMID: 17702769
Several chronic inflammatory disorders, such as systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA), and chronic infections that are associated with a chronic inflammatory state, such as human immunodeficiency virus...
5.
Homsma S, Lansberg P, Kastelein J
Ned Tijdschr Geneeskd
. 2004 Mar;
148(10):493-6.
PMID: 15042898
In the Netherlands, people with familial hypercholesterolaemia (FH) have been actively screened since 1994 by means of DNA analysis. Recently, the Stichting Opsporing Erfelijke Hypercholesterolemie (Foundation for the Detection of...
6.
van Vugt R, Kater L, Dijkstra P, Schardijn G, Kastelein J, Bijlsma J
Clin Exp Rheumatol
. 2003 Aug;
21(4):445-50.
PMID: 12942695
Objective: Upper extremity angiography can make an important contribution to the diagnosis in vasculopathy. The present study was designed to assess the diagnostic role of upper extremity angiography in patients...
7.
van der Valk M, Kastelein J, Murphy R, van Leth F, Katlama C, Horban A, et al.
AIDS
. 2001 Dec;
15(18):2407-14.
PMID: 11740191
Background: Protease inhibitor-containing antiretroviral therapy for the treatment of HIV-1 infection is associated with elevated triglyceride and low-density lipoprotein (LDL)-cholesterol levels which may expose patients to an increased risk of...
8.
Agema W, Jukema J, Pimstone S, Kastelein J
Eur Heart J
. 2001 Nov;
22(22):2058-74.
PMID: 11686664
No abstract available.
9.
Clee S, Loubser O, Collins J, Kastelein J, Hayden M
Clin Genet
. 2001 Oct;
60(4):293-300.
PMID: 11683775
Linkage of the lipoprotein lipase (LPL) gene to blood pressure levels has been reported. The LPL S447X single nucleotide polymorphism (cSNP) has been associated with decreased triglycerides (TG), increased high...
10.
Smilde T, van Wissen S, Wollersheim H, Kastelein J, Stalenhoef A
Neth J Med
. 2001 Oct;
59(4):184-95.
PMID: 11578794
Familial hypercholesterolemia is a hereditary metabolic disorder characterised by high low-density lipoprotein cholesterol levels and an extreme risk of premature cardiovascular disease. In patients with heterozygous familial hypercholesterolemia a substantial...