J J Clement
Overview
Explore the profile of J J Clement including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
46
Citations
332
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Kwok Y, Sun D, Clement J, Hurley L
Anticancer Drug Des
. 2000 Apr;
14(5):443-50.
PMID: 10766299
The quinobenzoxazine compounds, derived from antibacterial quinolones, is active in vitro and in vivo against murine and human tumors. In this contribution, we show that the relative DNA binding affinity...
2.
Gunawardana G, Rasmussen R, Scherr M, Frost D, Brandt K, Choi W, et al.
J Antibiot (Tokyo)
. 1997 Dec;
50(10):884-6.
PMID: 9402997
No abstract available.
3.
Hochlowski J, Jackson M, Rasmussen R, Buko A, Clement J, Whittern D, et al.
J Antibiot (Tokyo)
. 1997 Mar;
50(3):201-5.
PMID: 9127190
Several novel tiacumicin derivatives containing bromine have been produced by the addition of inorganic bromine to the fermentation both of Dactylosporangium aurantiacum subsp, hamdenensis. Structures were elucidated employing mass spectrometry...
4.
Chen R, Tennant S, Frost D, OBeirne M, Karwowski J, Humphrey P, et al.
J Antibiot (Tokyo)
. 1996 Jun;
49(6):596-8.
PMID: 8698645
No abstract available.
5.
Brill G, Kati W, Montgomery D, Karwowski J, Humphrey P, Jackson M, et al.
J Antibiot (Tokyo)
. 1996 Jun;
49(6):541-6.
PMID: 8698636
Two novel triterpene sulfates have been isolated from Fusarium compactum by bioactivity-directed fractionation using an assay which measures the inhibition of proteolytic activity of rhinovirus 3C protease on a fluorogenic...
6.
Alder J, Jarvis K, Marsh K, Klein L, Clement J
Br J Cancer
. 1996 Mar;
73(5):560-4.
PMID: 8605087
Two 9-dihydrotaxane analogues were synthesised and tested for in vitro potency and in vivo efficacy against murine and human tumour xenografts in mice. The in vitro potency of 9-dihydrotaxol (9-DH-t)...
7.
Brill G, Premachandran U, Karwowski J, Henry R, Cwik D, Traphagen L, et al.
J Antibiot (Tokyo)
. 1996 Feb;
49(2):124-8.
PMID: 8621350
The novel calcineurin inhibitor, dibefurin, has been isolated from the fungal culture AB 1650I-759. The isolation was bioactivity-directed fractionation using an assay which measures the phosphatase activity of calcineurin. The...
8.
Flamm R, Vojtko C, Chu D, Li Q, Beyer J, Hensey D, et al.
Antimicrob Agents Chemother
. 1995 Apr;
39(4):964-70.
PMID: 7786004
ABT-719 (A-86719.1) is the first compound of a new class of novel DNA gyrase inhibitors, the 2-pyridones, with potent antibacterial activity against gram-positive, gram-negative, and anaerobic organisms. ABT-719 was more...
9.
Clement J, Burres N, Jarvis K, Chu D, Swiniarski J, Alder J
Cancer Res
. 1995 Feb;
55(4):830-5.
PMID: 7850797
A-84441, a potent new antitumor quinolone, was active in vitro and in vivo against murine and human tumors. A-84441, a prodrug, was comparable in potency to the parent compound with...
10.
Permana P, Snapka R, Shen L, Chu D, Clement J, Plattner J
Biochemistry
. 1994 Sep;
33(37):11333-9.
PMID: 7727384
The antineoplastic quinobenoxazines A-62176 and A-74932 were shown to be potent inhibitors of mammalian DNA topoisomerase II in vivo. This was demonstrated by their selective inhibition of the SV40 DNA...