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J J Boelens

Explore the profile of J J Boelens including associated specialties, affiliations and a list of published articles. Areas
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Articles 39
Citations 472
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Recent Articles
11.
Admiraal R, Boelens J
Expert Opin Biol Ther . 2016 Mar; 16(6):801-13. PMID: 26959558
Introduction: The conditioning regimen used in cord blood transplantation (CBT) may significantly impact the outcomes. Variable pharmacokinetics (PK) of drugs used may further influence outcome. Individualized dosing takes inter-patient differences...
12.
Te Boome L, Mansilla C, van der Wagen L, Lindemans C, Petersen E, Spierings E, et al.
Leukemia . 2015 Apr; 29(9):1839-46. PMID: 25836589
We performed a prospective phase II study to evaluate clinical safety and outcome in 48 patients with steroid-refractory grade II-IV acute graft-versus-host disease (aGVHD) treated with mesenchymal stromal cells (MSCs)....
13.
Lawitschka A, Faraci M, Yaniv I, Veys P, Bader P, Wachowiak J, et al.
Bone Marrow Transplant . 2015 Jan; 50(4):592-7. PMID: 25621804
The aim of this analysis was to explore the diversity of reduced intensity conditioning (RIC) in paediatric allo-SCT in daily practice across Europe. Data from the European Group for Blood...
14.
Flinsenberg T, Spel L, Jansen M, Koning D, de Haar C, Plantinga M, et al.
J Virol . 2014 Nov; 89(2):1058-69. PMID: 25378489
Unlabelled: Reactivation of human cytomegalovirus (CMV) is hazardous to patients undergoing allogeneic cord blood transplantation (CBT), lowering survival rates by approximately 25%. While antiviral treatment ameliorates viremia, complete viral control...
15.
Hol J, Wolfs T, Bierings M, Lindemans C, Versluys A, Wildt de A, et al.
Bone Marrow Transplant . 2013 Oct; 49(1):95-101. PMID: 24121212
This study was aimed at finding predictors of invasive fungal infection (IFI) after pediatric allogeneic hematopoietic SCT (HSCT). All children who received allogeneic HSCT in the Wilhelmina Children's Hospital Utrecht...
16.
de Pagter P, Schuurman R, Keukens L, Schutten M, Cornelissen J, van Baarle D, et al.
Bone Marrow Transplant . 2013 Jun; 48(11):1460-4. PMID: 23771003
Hematopoietic SCT (HSCT) is often complicated by viral reactivations. In this retrospective cohort study (January 2004-August 2008), predictors for human herpes virus 6 (HHV6)-reactivation and associations between HHV6-reactivation and clinical...
17.
de Pagter P, Boelens J, Jacobi R, Schuurman R, Nanlohy N, Sanders E, et al.
Clin Immunol . 2013 May; 148(1):92-8. PMID: 23669455
Hematopoietic stem cell transplantation (HSCT) is frequently complicated by viral reactivations. Early diagnosis of viral reactivations and preemptive therapy relies on frequent viralload monitoring. An easy marker of effective cytotoxicity...
18.
Reubsaet L, de Pagter A, van Baarle D, Keukens L, Nanlohy N, Sanders E, et al.
Bone Marrow Transplant . 2012 Sep; 48(4):502-7. PMID: 23000652
In adult patients, regulatory CD4+FOXP3+ T cells are suggested to have a role in the control of allo-reactive disease after hematopoietic SCT (HSCT). We compared CD4+FOXP3+ T-cell reconstitution after unrelated...
19.
de Pagter A, Boelens J, Scherrenburg J, Vroom-de Blank T, Tesselaar K, Nanlohy N, et al.
Clin Immunol . 2012 Jul; 144(3):179-89. PMID: 22820131
Early human herpesvirus 6 (HHV6) reactivation after hematopoietic stem cell transplantation (HSCT) is associated with poor survival. We characterized HHV6 immuneresponses in HSCT patients during lymphopenia. Prospectively, HHV6 DNA-load was...
20.
van Egmond M, Vermeulen R, Peeters-Scholte C, Augoustides-Savvopoulou P, Abbink F, Boelens J, et al.
Neuropediatrics . 2011 Oct; 42(5):191-3. PMID: 21959744
Familial hemophagocytic lymphohistiocytosis (fHLH) is an autosomal recessive disorder characterized by proliferation and infiltration of several organs by activated lymphocytes and macrophages. Without allogeneic stem cell transplantation, fHLH is fatal....