J Hurwitz
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Explore the profile of J Hurwitz including associated specialties, affiliations and a list of published articles.
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323
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10688
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Recent Articles
11.
Lee C, Eki T, Okumura K, Nogami M, Soares V, Murakami Y, et al.
Somat Cell Mol Genet
. 2000 Aug;
25(1):33-9.
PMID: 10925702
RNA helicase A is the homolog of the Drosophila maleless protein, an essential factor involved in dosage compensation, and plays a crucial role in early development in mammals. Here, we...
12.
DeAngelis D, Hurwitz J, Shinoff M
Ophthalmic Plast Reconstr Surg
. 2000 Aug;
16(4):305-6.
PMID: 10923981
No abstract available.
13.
Sriskanda V, Kelman Z, Hurwitz J, Shuman S
Nucleic Acids Res
. 2000 Jun;
28(11):2221-8.
PMID: 10871342
We report the production, purification and characterization of a DNA ligase encoded by the thermophilic archaeon Methanobacterium thermoautotrophicum. The 561 amino acid MTH: ligase catalyzed strand-joining on a singly nicked...
14.
Ling X, Kamangar S, Boytim M, Kelman Z, Huie P, Lyu S, et al.
J Immunol
. 2000 Jun;
164(12):6188-92.
PMID: 10843669
Synthetic peptides corresponding to structural regions of HLA molecules are novel immunosuppressive agents. A peptide corresponding to residues 65-79 of the alpha-chain of HLA-DQA03011 (DQ65-79) blocks cell cycle progression from...
15.
Lee J, Hurwitz J
J Biol Chem
. 2000 Apr;
275(25):18871-8.
PMID: 10770926
Minichromosome maintenance (Mcm) proteins 2-7 are highly conserved in eukaryotes and play an essential role in DNA replication. Here, we describe the reconstitution of the various complexes of the Mcm...
16.
Chen X, Zuo S, Kelman Z, ODonnell M, Hurwitz J, Goodman M
J Biol Chem
. 2000 Apr;
275(23):17677-82.
PMID: 10748208
The fidelity of Schizosaccharomyces pombe DNA polymerase delta was measured in the presence or absence of its processivity subunits, proliferating cell nuclear antigen (PCNA) sliding clamp and replication factor C...
17.
Alleva J, Zuo S, Hurwitz J, Doetsch P
Biochemistry
. 2000 Mar;
39(10):2659-66.
PMID: 10704216
Schizosaccharomyces pombe alternative excision repair has been shown genetically and biochemically to be involved in the repair of a wide variety of DNA lesions. AER is initiated by a damage-specific...
18.
Kelman Z, Hurwitz J
J Biol Chem
. 2000 Mar;
275(10):7327-36.
PMID: 10702304
Replication factor C (RFC, also called activator 1), in conjunction with proliferating cell nuclear antigen (PCNA), is responsible for processive DNA synthesis catalyzed by the eukaryotic replicative DNA polymerases delta...
19.
Zuo S, Bermudez V, Zhang G, Kelman Z, Hurwitz J
J Biol Chem
. 2000 Feb;
275(7):5153-62.
PMID: 10671561
DNA polymerase delta (Pol delta) isolated from Schizosaccharomyces pombe (sp) consists of at least four subunits, Pol3, Cdc1, Cdc27, and Cdm1. We have reconstituted the four-subunit complex by simultaneously expressing...
20.
Yao N, Hurwitz J, ODonnell M
J Biol Chem
. 2000 Jan;
275(2):1421-32.
PMID: 10625694
Chromosomal replicases of cellular organisms utilize a ring shaped protein that encircles DNA as a mobile tether for high processivity in DNA synthesis. These "sliding clamps" have sufficiently large linear...