J H Wilton
Overview
Explore the profile of J H Wilton including associated specialties, affiliations and a list of published articles.
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33
Citations
336
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Recent Articles
1.
Luzier A, Killian A, Wilton J, Wilson M, Forrest A, Kazierad D
Clin Pharmacol Ther
. 1999 Dec;
66(6):594-601.
PMID: 10613615
Objective: To determine whether there are gender-specific differences in the pharmacokinetics and pharmacodynamics of metoprolol enantiomers. Methods: Twenty normal volunteers (10 men and 10 women) received 100 mg oral metoprolol...
2.
Lee S, Wu W, Wilton J, Beal J, Doskotch R
J Nat Prod
. 1999 Nov;
62(10):1410-4.
PMID: 10543903
Two benzyltetrahydroisoquinoline-protoberberine dimers, longiberine (1) and O-methyllongiberine (2), were isolated from the roots of Thalictrum longistylum and represent a new class of dimeric alkaloids. The structure of longiberine (1) was...
3.
Birmingham M, Guarino R, Heller A, Wilton J, Shah A, Hejmanowski L, et al.
J Antimicrob Chemother
. 1999 May;
43 Suppl A:43-8.
PMID: 10225571
Intravenous ciprofloxacin is frequently prescribed for the treatment of infections due to nosocomially acquired gram-negative organisms, including those originating in the respiratory tract. In this study, the concentrations of ciprofloxacin...
4.
Nix D, Thomas J, Symonds W, Spivey J, Wilton J, GAGLIARDI N, et al.
Ann Pharmacother
. 1997 Jun;
31(6):696-703.
PMID: 9184707
Objective: To determine the propensity of beta-lactam antimicrobials to ameliorate or potentiate aminoglycoside-induced renal enzymuria. Design: Two open, randomized, double-blind, parallel-group studies were conducted in young, healthy, male volunteer subjects....
5.
Nix D, Wilton J, Hyatt J, Thomas J, Forrest A, Schentag J
Antimicrob Agents Chemother
. 1997 May;
41(5):1108-14.
PMID: 9145877
The pharmacokinetics (PK) and pharmacodynamics (PD) of cefotaxime and ofloxacin and of their combination were examined in a three-period randomized crossover study involving 12 healthy adults. The PK of cefotaxime...
6.
Nix D, Symonds W, Hyatt J, Wilton J, Teal M, Reidenberg P, et al.
Pharmacotherapy
. 1997 Jan;
17(1):121-5.
PMID: 9017772
Study Objective: To compare the pharmacokinetics of ceftibuten, cefixime, ceturoxime axetil, and cefaclor after oral administration. Design: Randomized, four-period, crossover study. Setting: Hospital-based clinical research center. Subjects: Healthy adult men...
7.
Sowinski K, Forrest A, Wilton J, Taylor 2nd A, Wilson M, Kazierad D
J Clin Pharmacol
. 1995 Aug;
35(8):807-14.
PMID: 8522638
A study was conducted to characterize and compare the pharmacodynamics and pharmacokinetics of atenolol in young and elderly men. Six young (mean +/- SD, 25.0 +/- 3.0 years) and six...
8.
Huh K, Wilton J, Nix D, Schentag J
J Pharm Sci
. 1994 Jun;
83(6):763-7.
PMID: 9120803
Aminoglycosides and penicillins chemically interact when they are combined in vitro or in vivo. The resulting adducts are considered to be biologically inactive. The major adducts formed in he interaction...
9.
Paladino J, Forrest A, Wilton J
Pharmacotherapy
. 1993 Sep;
13(5):504-7.
PMID: 8247920
Patients enrolled in a fixed-dose clinical trial of oral ciprofloxacin had trough concentrations measured to document absorption and monitor compliance. The objective was to determine whether any demographic characteristics might...
10.
Perreault M, Kazierad D, Wilton J, Izzo Jr J
Pharmacotherapy
. 1993 Mar;
13(2):149-53.
PMID: 8469622
The effects of isradipine 2.5 mg and 5 mg on the disposition of theophylline were investigated in a placebo-controlled, randomized, three-way, crossover trial. Eleven healthy, nonsmoking men each received a...