J H van Delft
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Explore the profile of J H van Delft including associated specialties, affiliations and a list of published articles.
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41
Citations
189
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Recent Articles
1.
Jiang J, Mathijs K, Timmermans L, Claessen S, Hecka A, Weusten J, et al.
Data Brief
. 2017 Aug;
14:462-468.
PMID: 28831409
The inflammatory stress has been associated with an increase in susceptibility to idiosyncratic drug-induced liver injury (DILI). However, the molecular mechanisms of this inflammation-associated idiosyncratic drug hepatotoxicity remain unknown. We...
2.
Jiang J, Mathijs K, Timmermans L, Claessen S, Hecka A, Weusten J, et al.
Toxicol Appl Pharmacol
. 2017 Jul;
332:100-108.
PMID: 28733206
The mechanisms of idiosyncratic drug-induced hepatotoxicity remain largely unclear. It has demonstrated that the drug idiosyncrasy is potentiated in the context of inflammation and intracellular ceramides may play a role...
3.
van Delft J, Luiten-Schuite A, Souliotis V, Kyrtopoulos S, Ouwerkerk J, Keizer H, et al.
Biomarkers
. 2013 Jul;
1(2):94-8.
PMID: 23888919
Abstract Methyl-DNA adducts are induced by a number of lifestyle, environmental and occupational carcinogens, however knowledge about their kinetics is scarce. Here, N7-methylguanine (N7-MeGua) and O(6)-methylguanine (O(6)-MeGua) levels were determined...
4.
Oreffo V, Singh R, Rich K, Shuker D, Carthew P, Cordero R, et al.
Biomarkers
. 2013 Jul;
5(5):323-40.
PMID: 23886020
The formation of DNA adducts by the covalent binding of genotoxic chemicals to DNA represents a valuable marker for assessing exposure to carcinogens but as yet the role of DNA...
5.
Lizarraga D, Lozano C, Briede J, van Delft J, Tourino S, Centelles J, et al.
FEBS J
. 2007 Sep;
274(18):4802-11.
PMID: 17824958
Grape (Vitis vinifera) and pine (Pinus pinaster) bark extracts are widely used as nutritional supplements. Procyanidin-rich fractions from grape and pine bark extract showing different mean degrees of polymerization, percentage...
6.
van Delft J, Steenwinkel M, van Asten J, de Vogel N, Schouten T, Cramers P, et al.
Ann Occup Hyg
. 2001 Jun;
45(5):395-408.
PMID: 11418090
Unlabelled: Occupational exposure to polycyclic aromatic hydrocarbons (PAH) increases the risk of developing lung cancer. Human exposure is often demonstrated by increased internal levels of PAH metabolites and of markers...
7.
Pletsa V, Steenwinkel M, van Delft J, Baan R, Kyrtopoulos S
Cancer Lett
. 2000 Feb;
146(2):155-60.
PMID: 10656620
In order to examine the in vivo genotoxic activity of dichlorvos, lambdalacZ transgenic mice (Muta Mouse) were treated i.p. with single (4.4 or 11 mg/kg) or multiple (5 x 11...
8.
Turnbull D, Frankos V, van Delft J, DeVogel N
Regul Toxicol Pharmacol
. 1999 May;
29(2 Pt 1):205-10.
PMID: 10341152
Plant stanol esters from wood and vegetable oil sources were tested for genotoxicity in bacterial (Salmonella typhimurium) and mammalian cell (L5178Y) gene mutation assays and in a mammalian cell chromosome...
9.
Pletsa V, Steenwinkel M, van Delft J, Baan R, Kyrtopoulos S
Cancer Lett
. 1999 Mar;
135(1):21-7.
PMID: 10077217
Following single or multiple oral treatments of rats or lambda lacZ transgenic mice with methyl bromide, methylated DNA adducts (N7- and/or O6-methylguanine) were found at comparable levels in various tissues,...
10.
van Delft J, Baan R, Roza L
Crit Rev Toxicol
. 1998 Oct;
28(5):477-510.
PMID: 9793748
In this review data are summarized on biomarkers that are used for biological effect monitoring of human populations exposed to genotoxic carcinogens. The biomarkers are DNA and protein adducts and...