J H Nadeau
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Explore the profile of J H Nadeau including associated specialties, affiliations and a list of published articles.
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147
Citations
2770
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Recent Articles
1.
Sinasac D, Riordan J, Spiezio S, Yandell B, Croniger C, Nadeau J
Int J Obes (Lond)
. 2015 Sep;
40(2):346-55.
PMID: 26381349
Background/objectives: Both genetic and dietary factors contribute to the metabolic syndrome (MetS) in humans and animal models. Characterizing their individual roles as well as relationships among these factors is critical...
2.
Zechel J, MacLennan G, Heaney J, Nadeau J
Int J Androl
. 2011 Jun;
34(4 Pt 2):e278-87.
PMID: 21651572
Testicular germ-cell tumours (TGCTs) are the most common cancer in young men; the incidence is increasing worldwide and they have an unusually high rate of metastasis. Despite significant work on...
3.
Leussis M, Frayne M, Saito M, Berry E, Aldinger K, Rockwell G, et al.
Genes Brain Behav
. 2009 Aug;
8(8):806-16.
PMID: 19694817
Prepulse inhibition (PPI) is a measure of sensorimotor gating, a pre-attentional inhibitory brain mechanism that filters extraneous stimuli. Prepulse inhibition is correlated with measures of cognition and executive functioning, and...
4.
Matin A, Nadeau J
Trends Genet
. 2001 Nov;
17(12):727-31.
PMID: 11718927
Genetic variation in many biological processes and evolutionary adaptations is caused by polygenes--genes that act in combination to affect a particular trait. Despite the recent identification of several polygenes, many...
5.
Hoit B, Nadeau J
Trends Cardiovasc Med
. 2001 Sep;
11(2):82-9.
PMID: 11530297
Cardiovascular diseases such as hypertension, atherosclerosis, cardiac hypertrophy homocysteinemia and arrhythmias impose great health, social and financial costs. Some of these diseases are single gene traits that segregate in a...
6.
Robin N, Nadeau J
Am J Med Genet
. 2001 Jul;
101(4):334-8.
PMID: 11471156
Disorganization (Ds) is an autosomal dominant mouse mutant that produces a remarkable array of birth defects. So variable is the phenotype that no two mice appear identical. Ds also has...
7.
Nadeau J
Nat Rev Genet
. 2001 Mar;
2(3):165-74.
PMID: 11256068
An emerging theme of studies with spontaneous, engineered and induced mutant mice is that phenotypes often depend on genetic background, implying that genetic modifiers have a role in guiding the...
8.
Nadeau J, Balling R, Barsh G, Beier D, Brown S, Bucan M, et al.
Science
. 2001 Mar;
291(5507):1251-5.
PMID: 11233449
No abstract available.
9.
Jiang L, Nadeau J
Mamm Genome
. 2001 Feb;
12(2):89-94.
PMID: 11210194
Some forms of testicular germ cell tumors (TGCTs) arise from primordial germ cells (PGCs) during fetal development. In both humans and mice, genetic control of susceptibility is complex, involving both...
10.
Chadwick L, McCandless S, Silverman G, Schwartz S, Westaway D, Nadeau J
Genomics
. 2000 Nov;
70(1):66-73.
PMID: 11087663
Anomalies in folate and homocysteine metabolism can result in homocysteinemia and are implicated in disorders ranging from vascular disease to neural tube defects. Two enzymes are known to methylate homocysteine,...